Primary mouse brain pericytes isolated from transgenic Alzheimer mice spontaneously differentiate into a CD11b<sup>+</sup> microglial-like cell type in vitro.

Hutter-Schmid, Bianca; Humpel, Christian

Primary mouse brain pericytes isolated from transgenic Alzheimer mice spontaneously differentiate into a CD11b⁺ microglial-like cell type in vitro.

Hutter-Schmid, Bianca; Humpel, Christian.

Afiliação

Hutter-Schmid B; Laboratory of Psychiatry and Exp. Alzheimer's Research, Department of Psychiatry, Psychotherapy and Psychosomatics, Medical University of Innsbruck, Austria.
Humpel C; Laboratory of Psychiatry and Exp. Alzheimer's Research, Department of Psychiatry, Psychotherapy and Psychosomatics, Medical University of Innsbruck, Austria. Electronic address: christian.humpel@i-med.ac.at.

Exp Gerontol ; 112: 30-37, 2018 10 02.

Article em En | MEDLINE | ID: mdl-30099090

Assuntos

Doença de Alzheimer/metabolismo; Antígeno CD11b/metabolismo; Microglia/metabolismo; Pericitos/metabolismo; Animais; Astrócitos/patologia; Modelos Animais de Doenças; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Transgênicos; Neurônios/metabolismo; Pericitos/patologia

Palavras-chave

Alzheimer's disease; Amyloid-beta; CD11b(+); Differentiation; Microglia; Pericytes

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Microglia / Pericitos / Antígeno CD11b / Doença de Alzheimer Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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