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Design and synthesis of novel pyrimido[5,4-d]pyrimidine derivatives as GPR119 agonist for treatment of type 2 diabetes.
Fang, Yuanying; Xu, Jun; Li, Zhifeng; Yang, Zunhua; Xiong, Lijuan; Jin, Yi; Wang, Qi; Xie, Saisai; Zhu, Wufu; Chang, Sheng.
Afiliação
  • Fang Y; National Engineering Research Center for Manufacturing Technology of TCM Solid Preparation, Jiangxi University of Traditional Chinese Medicine, Nanchang 330006, China.
  • Xu J; College of Pharmacy, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China.
  • Li Z; National Engineering Research Center for Manufacturing Technology of TCM Solid Preparation, Jiangxi University of Traditional Chinese Medicine, Nanchang 330006, China.
  • Yang Z; College of Pharmacy, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China. Electronic address: joshyyy@126.com.
  • Xiong L; National Engineering Research Center for Manufacturing Technology of TCM Solid Preparation, Jiangxi University of Traditional Chinese Medicine, Nanchang 330006, China.
  • Jin Y; National Engineering Research Center for Manufacturing Technology of TCM Solid Preparation, Jiangxi University of Traditional Chinese Medicine, Nanchang 330006, China.
  • Wang Q; National Engineering Research Center for Manufacturing Technology of TCM Solid Preparation, Jiangxi University of Traditional Chinese Medicine, Nanchang 330006, China.
  • Xie S; National Engineering Research Center for Manufacturing Technology of TCM Solid Preparation, Jiangxi University of Traditional Chinese Medicine, Nanchang 330006, China.
  • Zhu W; College of Pharmacy, Jiangxi Science & Technology Normal University, Nanchang 330013, China.
  • Chang S; College of Pharmacy, Jilin Medical University, Jilin 132013, China. Electronic address: changsheng-pharm@hotmail.com.
Bioorg Med Chem ; 26(14): 4080-4087, 2018 08 07.
Article em En | MEDLINE | ID: mdl-30100020
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinas / Desenho de Fármacos / Receptores Acoplados a Proteínas G / Diabetes Mellitus Tipo 2 / Anti-Hipertensivos Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinas / Desenho de Fármacos / Receptores Acoplados a Proteínas G / Diabetes Mellitus Tipo 2 / Anti-Hipertensivos Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article