Complex lipid globules in early-life nutrition improve long-term metabolic phenotype in intra-uterine growth-restricted rats.

Teller, Inga C; Hoyer-Kuhn, Heike; Brönneke, Hella; Nosthoff-Horstmann, Pia; Oosting, Annemarie; Lippach, Gregor; Wohlfarth, Maria; Rauh, Manfred; van der Beek, Eline M; Dötsch, Jörg; Nüsken, Kai D

Teller, Inga C; Hoyer-Kuhn, Heike; Brönneke, Hella; Nosthoff-Horstmann, Pia; Oosting, Annemarie; Lippach, Gregor; Wohlfarth, Maria; Rauh, Manfred; van der Beek, Eline M; Dötsch, Jörg; Nüsken, Kai D.

Afiliação

Teller IC; 1Nutricia Research,3508 TC Utrecht,The Netherlands.
Hoyer-Kuhn H; 2Department of Pediatrics and Adolescent Medicine,Medical Faculty,University of Cologne,50937 Cologne,Germany.
Brönneke H; 3Mouse Phenotyping Core Facility,Cologne Excellence Cluster on Cellular Stress Responses (CECAD),50931 Cologne,Germany.
Nosthoff-Horstmann P; 2Department of Pediatrics and Adolescent Medicine,Medical Faculty,University of Cologne,50937 Cologne,Germany.
Oosting A; 1Nutricia Research,3508 TC Utrecht,The Netherlands.
Lippach G; 2Department of Pediatrics and Adolescent Medicine,Medical Faculty,University of Cologne,50937 Cologne,Germany.
Wohlfarth M; 2Department of Pediatrics and Adolescent Medicine,Medical Faculty,University of Cologne,50937 Cologne,Germany.
Rauh M; 4Department of Pediatrics,University of Erlangen-Nuremberg,91054 Erlangen,Germany.
van der Beek EM; 1Nutricia Research,3508 TC Utrecht,The Netherlands.
Dötsch J; 2Department of Pediatrics and Adolescent Medicine,Medical Faculty,University of Cologne,50937 Cologne,Germany.
Nüsken KD; 2Department of Pediatrics and Adolescent Medicine,Medical Faculty,University of Cologne,50937 Cologne,Germany.

Br J Nutr ; 120(7): 763-776, 2018 10.

Article em En | MEDLINE | ID: mdl-30109842

Assuntos

Glicemia/metabolismo; Dieta; Gorduras na Dieta/farmacologia; Retardo do Crescimento Fetal/metabolismo; Fenômenos Fisiológicos da Nutrição do Lactente; Gordura Intra-Abdominal/metabolismo; Lipídeos/farmacologia; Animais; Biomarcadores/metabolismo; Dieta Ocidental; Gorduras na Dieta/administração & dosagem; Gorduras na Dieta/metabolismo; Feminino; Humanos; Lactente; Proteína 1 de Ligação a Fator de Crescimento Semelhante à Insulina/metabolismo; Leptina/sangue; Ligadura; Metabolismo dos Lipídeos/efeitos dos fármacos; Lipídeos/administração & dosagem; Lipídeos/sangue; Fígado/efeitos dos fármacos; Fígado/metabolismo; Masculino; Mesentério; Gravidez; Ratos Wistar; Triglicerídeos/sangue; Útero/cirurgia

Palavras-chave

AIN American Institute of Nutrition; CLM complex lipid matrix (intervention diet); CTRL normal matrix control diet; HM human milk; IF infant milk formula; IGF-1 insulin-like growth factor 1; IUGR intra-uterine growth restriction; LEP leptin gene; LIG ligation (uterine vessel ligation group); MFG milk fat globule; MFGM MFG membrane; NOP non-operated (control group); PL phospholipids; PND postnatal day; SOP sham operation (SOP group i.e. intra-uterine stress group); WSD Western-style diet ('challenge' diet); µCT micro computer tomograph; Intra-uterine growth restriction; Leptin; Metabolic programming; Milk fat globules; Visceral fat mass

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glicemia / Gorduras na Dieta / Dieta / Gordura Intra-Abdominal / Retardo do Crescimento Fetal / Fenômenos Fisiológicos da Nutrição do Lactente / Lipídeos Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Infant / Male / Pregnancy Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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