Identification of Positively and Negatively Selected Driver Gene Mutations Associated With Colorectal Cancer With Microsatellite Instability.
Cell Mol Gastroenterol Hepatol
; 6(3): 277-300, 2018.
Article
em En
| MEDLINE
| ID: mdl-30116770
Palavras-chave
CRC, colorectal cancer; Colorectal Cancer; Driver Gene Mutations; HR, hazard ratio; MLH1, MutL Homolog 1; MMR, mismatch repair; MSH, MutS Homolog; MSI, microsatellite instability; Microsatellite Instability; NR, nonrepetitive; PBS, phosphate-buffered saline; PCR, polymerase chain reaction; Positive and Negative Selection; R, repetitive; RFS, relapse-free survival; RTCA, Real-Time Cell Analyzer; Tumorigenic Process; UTR, untranslated region; WES, whole-exome sequencing; WGA, whole-genome amplification; bp, base pair; indel, insertion/deletion; mRNA, messenger RNA; shRNA, short hairpin RNA; siRNA, small interfering RNA
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Sequências Repetitivas de Ácido Nucleico
/
Neoplasias Colorretais
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Instabilidade de Microssatélites
/
Carcinogênese
/
Mutação
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Incidence_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Animals
/
Female
/
Humans
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Male
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article