Cobalt Octacarbonyl-Catalyzed Scalable Alkyne Cyclotrimerization and Crossed [2 + 2 + 2]-Cycloaddition Reaction in a Plug Flow Reactor.
Org Lett
; 20(17): 5219-5223, 2018 09 07.
Article
em En
| MEDLINE
| ID: mdl-30125114
ABSTRACT
Cobalt-catalyzed alkyne cyclotrimerization and crossed [2 + 2 + 2] cycloadditions are developed in a plug flow reactor. The protocol generally uses 5 mol % of Co2(CO)8 and is scalable at least at multigram scale. Efficient and scalable use of Co2(CO)8 for crossed reactions of diynes and alkynes has hardly any precedent.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article