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Enthalpy-Driven Stabilization of Transthyretin by AG10 Mimics a Naturally Occurring Genetic Variant That Protects from Transthyretin Amyloidosis.
Miller, Mark; Pal, Arindom; Albusairi, Wabel; Joo, Hyun; Pappas, Beverly; Haque Tuhin, Md Tariqul; Liang, Dengpan; Jampala, Raghavendra; Liu, Fang; Khan, Jared; Faaij, Marjon; Park, Miki; Chan, William; Graef, Isabella; Zamboni, Robert; Kumar, Neil; Fox, Jonathan; Sinha, Uma; Alhamadsheh, Mamoun.
Afiliação
  • Miller M; Department of Pharmaceutics & Medicinal Chemistry , University of the Pacific , Stockton , California 95211 , United States.
  • Pal A; Department of Pharmaceutics & Medicinal Chemistry , University of the Pacific , Stockton , California 95211 , United States.
  • Albusairi W; Department of Pharmaceutics & Medicinal Chemistry , University of the Pacific , Stockton , California 95211 , United States.
  • Joo H; Department of Pharmaceutics & Medicinal Chemistry , University of the Pacific , Stockton , California 95211 , United States.
  • Pappas B; Department of Pharmaceutics & Medicinal Chemistry , University of the Pacific , Stockton , California 95211 , United States.
  • Haque Tuhin MT; Department of Pharmaceutics & Medicinal Chemistry , University of the Pacific , Stockton , California 95211 , United States.
  • Liang D; Department of Pharmaceutics & Medicinal Chemistry , University of the Pacific , Stockton , California 95211 , United States.
  • Jampala R; Department of Pharmaceutics & Medicinal Chemistry , University of the Pacific , Stockton , California 95211 , United States.
  • Liu F; Department of Pharmaceutics & Medicinal Chemistry , University of the Pacific , Stockton , California 95211 , United States.
  • Khan J; Department of Pharmaceutics & Medicinal Chemistry , University of the Pacific , Stockton , California 95211 , United States.
  • Faaij M; Department of Pharmaceutics & Medicinal Chemistry , University of the Pacific , Stockton , California 95211 , United States.
  • Park M; Department of Pharmaceutics & Medicinal Chemistry , University of the Pacific , Stockton , California 95211 , United States.
  • Chan W; Department of Pharmaceutics & Medicinal Chemistry , University of the Pacific , Stockton , California 95211 , United States.
  • Graef I; Department of Pathology , Stanford University , Stanford , California 94305 , United States.
  • Zamboni R; Eidos Therapeutics, Inc. , San Francisco , California 94101 , United States.
  • Kumar N; Eidos Therapeutics, Inc. , San Francisco , California 94101 , United States.
  • Fox J; Eidos Therapeutics, Inc. , San Francisco , California 94101 , United States.
  • Sinha U; Eidos Therapeutics, Inc. , San Francisco , California 94101 , United States.
  • Alhamadsheh M; Department of Pharmaceutics & Medicinal Chemistry , University of the Pacific , Stockton , California 95211 , United States.
J Med Chem ; 61(17): 7862-7876, 2018 09 13.
Article em En | MEDLINE | ID: mdl-30133284
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazóis / Benzoatos / Pré-Albumina / Neuropatias Amiloides Familiares / Mutação Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazóis / Benzoatos / Pré-Albumina / Neuropatias Amiloides Familiares / Mutação Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article