Pheniramine maleate: an apparently safe drug causing bullous fixed drug eruption.
Dermatol Online J
; 24(6)2018 08 23.
Article
em En
| MEDLINE
| ID: mdl-30142724
ABSTRACT
Fixed drug eruption is a delayed type hypersensitivity reaction to a drug seen most frequently with antibiotics such as tetracyclines, sulfonamides, and NSAIDs such as naproxen and ibuprofen. Although H1-antihistamines rarely elicit cutaneous adverse effects, there have been a few reports in the literature implicating them in causing fixed drug eruption, particularly the piperazine derivatives (hydroxyzine, cetirizine, levocetirizine), and loratadine. However, cutaneous drug reactions with the alkylamine derivatives like pheniramine maleate are extremely uncommon and fixed drug eruptions have not been reported with any of the alkylamine antihistamines to date. We herein report a case of multifocal bullous fixed drug eruption following ingestion of pheniramine maleate.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Feniramina
/
Infecções Respiratórias
/
Dermatopatias Vesiculobolhosas
/
Toxidermias
/
Antagonistas dos Receptores Histamínicos H1
Limite:
Adult
/
Female
/
Humans
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article