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HiGlass: web-based visual exploration and analysis of genome interaction maps.
Kerpedjiev, Peter; Abdennur, Nezar; Lekschas, Fritz; McCallum, Chuck; Dinkla, Kasper; Strobelt, Hendrik; Luber, Jacob M; Ouellette, Scott B; Azhir, Alaleh; Kumar, Nikhil; Hwang, Jeewon; Lee, Soohyun; Alver, Burak H; Pfister, Hanspeter; Mirny, Leonid A; Park, Peter J; Gehlenborg, Nils.
Afiliação
  • Kerpedjiev P; Department of Biomedical Informatics, Harvard Medical School, Countway Library, 10 Shattuck St, Boston, MA, 02115, USA.
  • Abdennur N; Computational and Systems Biology Program, MIT, Cambridge, USA.
  • Lekschas F; School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.
  • McCallum C; Department of Biomedical Informatics, Harvard Medical School, Countway Library, 10 Shattuck St, Boston, MA, 02115, USA.
  • Dinkla K; School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.
  • Strobelt H; School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.
  • Luber JM; Department of Biomedical Informatics, Harvard Medical School, Countway Library, 10 Shattuck St, Boston, MA, 02115, USA.
  • Ouellette SB; Bioinformatics and Integrative Genomics Program, Harvard Medical School, Boston, MA, USA.
  • Azhir A; Department of Biomedical Informatics, Harvard Medical School, Countway Library, 10 Shattuck St, Boston, MA, 02115, USA.
  • Kumar N; Department of Biomedical Informatics, Harvard Medical School, Countway Library, 10 Shattuck St, Boston, MA, 02115, USA.
  • Hwang J; Department of Biomedical Informatics, Harvard Medical School, Countway Library, 10 Shattuck St, Boston, MA, 02115, USA.
  • Lee S; School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.
  • Alver BH; Department of Biomedical Informatics, Harvard Medical School, Countway Library, 10 Shattuck St, Boston, MA, 02115, USA.
  • Pfister H; Department of Biomedical Informatics, Harvard Medical School, Countway Library, 10 Shattuck St, Boston, MA, 02115, USA.
  • Mirny LA; School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.
  • Park PJ; Department of Physics, MIT, Cambridge, USA.
  • Gehlenborg N; Institute for Medical Engineering and Science, MIT, Cambridge, USA.
Genome Biol ; 19(1): 125, 2018 08 24.
Article em En | MEDLINE | ID: mdl-30143029
ABSTRACT
We present HiGlass, an open source visualization tool built on web technologies that provides a rich interface for rapid, multiplex, and multiscale navigation of 2D genomic maps alongside 1D genomic tracks, allowing users to combine various data types, synchronize multiple visualization modalities, and share fully customizable views with others. We demonstrate its utility in exploring different experimental conditions, comparing the results of analyses, and creating interactive snapshots to share with collaborators and the broader public. HiGlass is accessible online at http//higlass.io and is also available as a containerized application that can be run on any platform.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Mapeamento Cromossômico / Genoma / Internet Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Mapeamento Cromossômico / Genoma / Internet Idioma: En Ano de publicação: 2018 Tipo de documento: Article