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The discovery of Bombali virus adds further support for bats as hosts of ebolaviruses.
Goldstein, Tracey; Anthony, Simon J; Gbakima, Aiah; Bird, Brian H; Bangura, James; Tremeau-Bravard, Alexandre; Belaganahalli, Manjunatha N; Wells, Heather L; Dhanota, Jasjeet K; Liang, Eliza; Grodus, Michael; Jangra, Rohit K; DeJesus, Veronica A; Lasso, Gorka; Smith, Brett R; Jambai, Amara; Kamara, Brima O; Kamara, Sorie; Bangura, William; Monagin, Corina; Shapira, Sagi; Johnson, Christine K; Saylors, Karen; Rubin, Edward M; Chandran, Kartik; Lipkin, W Ian; Mazet, Jonna A K.
Afiliação
  • Goldstein T; One Health Institute & Karen C. Drayer Wildlife Health Center, School of Veterinary Medicine, University of California, Davis, CA, USA. tgoldstein@ucdavis.edu.
  • Anthony SJ; Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY, USA. sja2127@cumc.columbia.edu.
  • Gbakima A; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA. sja2127@cumc.columbia.edu.
  • Bird BH; EcoHealth Alliance, New York, NY, USA. sja2127@cumc.columbia.edu.
  • Bangura J; Metabiota, Inc. Sierra Leone, Freetown, Sierra Leone.
  • Tremeau-Bravard A; One Health Institute & Karen C. Drayer Wildlife Health Center, School of Veterinary Medicine, University of California, Davis, CA, USA.
  • Belaganahalli MN; Metabiota, Inc. Sierra Leone, Freetown, Sierra Leone.
  • Wells HL; One Health Institute & Karen C. Drayer Wildlife Health Center, School of Veterinary Medicine, University of California, Davis, CA, USA.
  • Dhanota JK; One Health Institute & Karen C. Drayer Wildlife Health Center, School of Veterinary Medicine, University of California, Davis, CA, USA.
  • Liang E; Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY, USA.
  • Grodus M; One Health Institute & Karen C. Drayer Wildlife Health Center, School of Veterinary Medicine, University of California, Davis, CA, USA.
  • Jangra RK; Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY, USA.
  • DeJesus VA; EcoHealth Alliance, New York, NY, USA.
  • Lasso G; Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY, USA.
  • Smith BR; Department of Microbiology and Immunology, Albert Einstein College of Medicine, New York, NY, USA.
  • Jambai A; Department of Microbiology and Immunology, Albert Einstein College of Medicine, New York, NY, USA.
  • Kamara BO; Department of Systems Biology, Irving Cancer Research Center, Columbia University, New York, NY, USA.
  • Kamara S; One Health Institute & Karen C. Drayer Wildlife Health Center, School of Veterinary Medicine, University of California, Davis, CA, USA.
  • Bangura W; Ministry of Health and Sanitation, Freetown, Sierra Leone.
  • Monagin C; Ministry of Health and Sanitation, Makeni, Sierra Leone.
  • Shapira S; Livestock and Veterinary Services Division, Ministry of Agriculture, Forestry and Food Security, Freetown, Sierra Leone.
  • Johnson CK; Forestry and Wildlife Division, Ministry of Agriculture, Forestry and Food Security, Freetown, Sierra Leone.
  • Saylors K; One Health Institute & Karen C. Drayer Wildlife Health Center, School of Veterinary Medicine, University of California, Davis, CA, USA.
  • Rubin EM; Metabiota, Inc., San Francisco, CA, USA.
  • Chandran K; Department of Systems Biology, Irving Cancer Research Center, Columbia University, New York, NY, USA.
  • Lipkin WI; Department of Microbiology & Immunology, Columbia University, New York, NY, USA.
  • Mazet JAK; One Health Institute & Karen C. Drayer Wildlife Health Center, School of Veterinary Medicine, University of California, Davis, CA, USA.
Nat Microbiol ; 3(10): 1084-1089, 2018 10.
Article em En | MEDLINE | ID: mdl-30150734
ABSTRACT
Here we describe the complete genome of a new ebolavirus, Bombali virus (BOMV) detected in free-tailed bats in Sierra Leone (little free-tailed (Chaerephon pumilus) and Angolan free-tailed (Mops condylurus)). The bats were found roosting inside houses, indicating the potential for human transmission. We show that the viral glycoprotein can mediate entry into human cells. However, further studies are required to investigate whether exposure has actually occurred or if BOMV is pathogenic in humans.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quirópteros / Ebolavirus Limite: Animals / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quirópteros / Ebolavirus Limite: Animals / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article