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Design, synthesis and biological evaluation of a novel library of antimitotic C2-aroyl/arylimino tryptamine derivatives that are also potent inhibitors of indoleamine-2, 3-dioxygenase (IDO).
Chauhan, Jyoti; Dasgupta, Moumita; Luthra, Tania; Awasthi, Akanksha; Tripathy, Sayantan; Banerjee, Anindyajit; Paul, Santanu; Nag, Debasish; Chakrabarti, Saikat; Chakrabarti, Gopal; Sen, Subhabrata.
Afiliação
  • Chauhan J; Department of Chemistry, School of Natural Sciences, Shiv Nadar University, Dadri, Chithera, Gautambudh Nagar, UP 201314, India.
  • Dasgupta M; Department of Biotechnology and Dr B.C. Guha Centre for Genetic, Engineering and Biotechnology, University of Calcutta, 35 Ballygunge Circular Road, Kolkata, WB 700019, India.
  • Luthra T; Department of Chemistry, School of Natural Sciences, Shiv Nadar University, Dadri, Chithera, Gautambudh Nagar, UP 201314, India.
  • Awasthi A; Department of Chemistry, School of Natural Sciences, Shiv Nadar University, Dadri, Chithera, Gautambudh Nagar, UP 201314, India.
  • Tripathy S; Department of Chemistry, School of Natural Sciences, Shiv Nadar University, Dadri, Chithera, Gautambudh Nagar, UP 201314, India.
  • Banerjee A; Structural Biology and Bio-Informatics Division, CSIR-Indian Institute of Chemical Biology, 4, Raja SC Mullick Road, Kolkata, West Bengal 700032, India.
  • Paul S; Department of Biotechnology and Dr B.C. Guha Centre for Genetic, Engineering and Biotechnology, University of Calcutta, 35 Ballygunge Circular Road, Kolkata, WB 700019, India.
  • Nag D; Department of Biotechnology and Dr B.C. Guha Centre for Genetic, Engineering and Biotechnology, University of Calcutta, 35 Ballygunge Circular Road, Kolkata, WB 700019, India.
  • Chakrabarti S; Structural Biology and Bio-Informatics Division, CSIR-Indian Institute of Chemical Biology, 4, Raja SC Mullick Road, Kolkata, West Bengal 700032, India.
  • Chakrabarti G; Department of Biotechnology and Dr B.C. Guha Centre for Genetic, Engineering and Biotechnology, University of Calcutta, 35 Ballygunge Circular Road, Kolkata, WB 700019, India.
  • Sen S; Department of Chemistry, School of Natural Sciences, Shiv Nadar University, Dadri, Chithera, Gautambudh Nagar, UP 201314, India; Department of Chemistry, SRM University-AP, Amaravati, Andhra Pradesh 52202, India. Electronic address: subhabrata.sen@snu.edu.in.
Eur J Pharm Sci ; 124: 249-265, 2018 Nov 01.
Article em En | MEDLINE | ID: mdl-30170210

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Triptaminas / Dioxigenases / Antimitóticos / Moduladores de Tubulina Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Triptaminas / Dioxigenases / Antimitóticos / Moduladores de Tubulina Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article