A Promising Small Molecule for Vanishing White Matter Disease.

Mithal, Divakar S; Rubin, Jennifer P

Mithal, Divakar S; Rubin, Jennifer P.

Afiliação

Mithal DS; Division of Neurology, Department of Pediatrics, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL.
Rubin JP; Division of Neurology, Department of Pediatrics, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL.

Pediatr Neurol Briefs ; 32: 5, 2018 Aug 28.

Article em En | MEDLINE | ID: mdl-30174381

ABSTRACT

ABSTRACT

Investigators from Calico Life Sciences LLC and AbbVie report the effects of a novel drug targeting the genetic basis of Vanishing White Matter Disease (VWMD).

Palavras-chave

Chemical Biology; Integrated Stress Response; Translation Initiation; Vanishing White Matter Disease; eIF2B

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2018 Tipo de documento: Article