Application of different pharmacokinetic models to describe and predict pharmacokinetics of voriconazole in magellanic penguins following oral administration.

Parsley, Ruth A; Mutlow, Adrian G; Hansted, Jacqueline; Taverne, Femke J; Tell, Lisa A; Gehring, Ronette

Parsley, Ruth A; Mutlow, Adrian G; Hansted, Jacqueline; Taverne, Femke J; Tell, Lisa A; Gehring, Ronette.

Afiliação

Parsley RA; Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, California.
Mutlow AG; San Francisco Zoo, San Francisco, California.
Hansted J; San Francisco Zoo, San Francisco, California.
Taverne FJ; Veterinary Pharmacotherapeutics and Pharmacy Group, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands.
Tell LA; Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, California.
Gehring R; Veterinary Pharmacotherapeutics and Pharmacy Group, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands.

J Vet Pharmacol Ther ; 42(1): 74-84, 2019 Jan.

Article em En | MEDLINE | ID: mdl-30175535

Assuntos

Antifúngicos/farmacocinética; Spheniscidae/metabolismo; Voriconazol/farmacocinética; Administração Oral; Animais; Antifúngicos/administração & dosagem; Antifúngicos/sangue; Cromatografia Líquida de Alta Pressão/veterinária; Relação Dose-Resposta a Droga; Feminino; Meia-Vida; Masculino; Modelos Biológicos; Spheniscidae/sangue; Voriconazol/administração & dosagem; Voriconazol/sangue

Palavras-chave

aspergillosis; modeling; penguins; pharmacokinetics; voriconazole

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Spheniscidae / Voriconazol / Antifúngicos Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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