The amyloid precursor protein binds to ß-catenin and modulates its cellular distribution.

Zhang, Ningyu; Parr, Callum J C; Birch, Amy M; Goldfinger, Marc H; Sastre, Magdalena

Zhang, Ningyu; Parr, Callum J C; Birch, Amy M; Goldfinger, Marc H; Sastre, Magdalena.

Afiliação

Zhang N; Division of Brain Sciences, Department of Medicine, Imperial College London, Hammersmith Hospital, Du Cane Road, London, W12 ONN, United Kingdom.
Parr CJC; Division of Brain Sciences, Department of Medicine, Imperial College London, Hammersmith Hospital, Du Cane Road, London, W12 ONN, United Kingdom.
Birch AM; Division of Brain Sciences, Department of Medicine, Imperial College London, Hammersmith Hospital, Du Cane Road, London, W12 ONN, United Kingdom.
Goldfinger MH; Division of Brain Sciences, Department of Medicine, Imperial College London, Hammersmith Hospital, Du Cane Road, London, W12 ONN, United Kingdom.
Sastre M; Division of Brain Sciences, Department of Medicine, Imperial College London, Hammersmith Hospital, Du Cane Road, London, W12 ONN, United Kingdom. Electronic address: m.sastre@imperial.ac.uk.

Neurosci Lett ; 685: 190-195, 2018 10 15.

Article em En | MEDLINE | ID: mdl-30176342

Assuntos

Doença de Alzheimer/genética; Precursor de Proteína beta-Amiloide/metabolismo; Via de Sinalização Wnt/fisiologia; beta Catenina/metabolismo; Precursor de Proteína beta-Amiloide/genética; Animais; Núcleo Celular/metabolismo; Quinase 3 da Glicogênio Sintase/metabolismo; Camundongos; Fosforilação; Via de Sinalização Wnt/genética

Palavras-chave

Alzheimer's disease; Amyloid precursor protein (APP); GSK3; Wnt pathway; ß-catenin

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Precursor de Proteína beta-Amiloide / Beta Catenina / Doença de Alzheimer / Via de Sinalização Wnt Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google