The effect of ethylene oxide sterilization on electrospun vascular grafts made from biodegradable polyesters.
Mater Sci Eng C Mater Biol Appl
; 92: 132-142, 2018 Nov 01.
Article
em En
| MEDLINE
| ID: mdl-30184736
The study describes the detailed examination of the effect of ethylene oxide sterilization on electrospun scaffolds constructed from biodegradable polyesters. Different fibrous layers fabricated from polycaprolactone (PCL) and a copolymer consisting of polylactide and polycaprolactone (PLCL) were investigated for the determination of their mechanical properties, degradation rates and interaction with fibroblasts. It was discovered that the sterilization procedure influenced the mechanical properties of the electrospun PLCL copolymer scaffold to the greatest extent. No effect of ethylene oxide sterilization on degradation behavior was observed. However, a delayed fibroblast proliferation rate was noticed with concern to the ethylene oxide sterilized samples compared to the ethanol sterilization of the materials.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Poliésteres
/
Materiais Biocompatíveis
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Óxido de Etileno
Limite:
Animals
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article