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The effect of ethylene oxide sterilization on electrospun vascular grafts made from biodegradable polyesters.
Horakova, J; Mikes, P; Saman, A; Jencova, V; Klapstova, A; Svarcova, T; Ackermann, M; Novotny, V; Suchy, T; Lukas, D.
Afiliação
  • Horakova J; Department of Nonwovens and Nanofibrous Materials, Faculty of Textile Engineering, Technical University of Liberec, Studentska 1402/2, 461 17 Liberec, Czech Republic. Electronic address: jana.horakova@tul.cz.
  • Mikes P; Department of Nonwovens and Nanofibrous Materials, Faculty of Textile Engineering, Technical University of Liberec, Studentska 1402/2, 461 17 Liberec, Czech Republic. Electronic address: petr.mikes@tul.cz.
  • Saman A; Department of Nonwovens and Nanofibrous Materials, Faculty of Textile Engineering, Technical University of Liberec, Studentska 1402/2, 461 17 Liberec, Czech Republic. Electronic address: ales.saman@tul.cz.
  • Jencova V; Department of Nonwovens and Nanofibrous Materials, Faculty of Textile Engineering, Technical University of Liberec, Studentska 1402/2, 461 17 Liberec, Czech Republic. Electronic address: vera.jencova@tul.cz.
  • Klapstova A; Department of Nonwovens and Nanofibrous Materials, Faculty of Textile Engineering, Technical University of Liberec, Studentska 1402/2, 461 17 Liberec, Czech Republic. Electronic address: andrea.klapstova@tul.cz.
  • Svarcova T; Department of Nonwovens and Nanofibrous Materials, Faculty of Textile Engineering, Technical University of Liberec, Studentska 1402/2, 461 17 Liberec, Czech Republic. Electronic address: tereza.svarcova@tul.cz.
  • Ackermann M; Department of Industrial Technology, Institute of Nanomaterials, Advanced Technologies and Innovation, Technical University of Liberec, Studentska 1402/2, 460 01 Liberec, Czech Republic. Electronic address: michal.ackermann@tul.cz.
  • Novotny V; Department of Nanomaterials in Natural Sciences, Institute of Nanomaterials, Advanced Technologies and Innovation, Technical University of Liberec, Liberec, Czech Republic. Electronic address: vit.novotny@tul.cz.
  • Suchy T; The Czech Academy of Sciences, Institute of Rock Structure and Mechanics, V Holesovickach 94/41, 182 09 Prague, Czech Republic. Electronic address: suchyt@irsm.cas.cz.
  • Lukas D; Department of Nonwovens and Nanofibrous Materials, Faculty of Textile Engineering, Technical University of Liberec, Studentska 1402/2, 461 17 Liberec, Czech Republic. Electronic address: david.lukas@tul.cz.
Mater Sci Eng C Mater Biol Appl ; 92: 132-142, 2018 Nov 01.
Article em En | MEDLINE | ID: mdl-30184736
The study describes the detailed examination of the effect of ethylene oxide sterilization on electrospun scaffolds constructed from biodegradable polyesters. Different fibrous layers fabricated from polycaprolactone (PCL) and a copolymer consisting of polylactide and polycaprolactone (PLCL) were investigated for the determination of their mechanical properties, degradation rates and interaction with fibroblasts. It was discovered that the sterilization procedure influenced the mechanical properties of the electrospun PLCL copolymer scaffold to the greatest extent. No effect of ethylene oxide sterilization on degradation behavior was observed. However, a delayed fibroblast proliferation rate was noticed with concern to the ethylene oxide sterilized samples compared to the ethanol sterilization of the materials.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Poliésteres / Materiais Biocompatíveis / Óxido de Etileno Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Poliésteres / Materiais Biocompatíveis / Óxido de Etileno Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article