Differential assembly of Rous sarcoma virus tetrameric and octameric intasomes is regulated by the C-terminal domain and tail region of integrase.

Bera, Sibes; Pandey, Krishan K; Aihara, Hideki; Grandgenett, Duane P

Bera, Sibes; Pandey, Krishan K; Aihara, Hideki; Grandgenett, Duane P.

Afiliação

Bera S; From the Department of Molecular Microbiology and Immunology, Institute for Molecular Virology, Saint Louis University Health Sciences Center, Saint Louis, Missouri 63104 and.
Pandey KK; From the Department of Molecular Microbiology and Immunology, Institute for Molecular Virology, Saint Louis University Health Sciences Center, Saint Louis, Missouri 63104 and.
Aihara H; the Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota 55455.
Grandgenett DP; From the Department of Molecular Microbiology and Immunology, Institute for Molecular Virology, Saint Louis University Health Sciences Center, Saint Louis, Missouri 63104 and Duane.Grandgenett@health.slu.edu.

J Biol Chem ; 293(42): 16440-16452, 2018 10 19.

Article em En | MEDLINE | ID: mdl-30185621

Assuntos

DNA Viral/metabolismo; Integrases/metabolismo; Vírus do Sarcoma de Rous/química; Integração Viral; Animais; Integrases/química; Multimerização Proteica; Sequências Repetidas Terminais

Palavras-chave

DNA enzyme; DNAprotein interaction; HIV; Rous sarcoma virus; human immunodeficiency virus (HIV); intasome; integrase; integrase tetrameric and octameric stable synaptic complex; retrovirus; strand-transfer complex; strand-transfer inhibitors; viral integration

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: DNA Viral / Integração Viral / Integrases / Vírus do Sarcoma de Rous Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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