Evaluating the Accelerated Blood Clearance Phenomenon of PEGylated Nanoemulsions in Rats by Intraperitoneal Administration.

Su, Yuqing; Liu, Mengyang; Liang, Kaifan; Liu, Xinrong; Song, Yanzhi; Deng, Yihui

Su, Yuqing; Liu, Mengyang; Liang, Kaifan; Liu, Xinrong; Song, Yanzhi; Deng, Yihui.

Afiliação

Su Y; School of Pharmacy, Shenyang Pharmaceutical University, 26 Huatuo Road, Benxi, 117004, People's Republic of China.
Liu M; School of Pharmacy, Shenyang Pharmaceutical University, 26 Huatuo Road, Benxi, 117004, People's Republic of China.
Liang K; School of Pharmacy, Shenyang Pharmaceutical University, 26 Huatuo Road, Benxi, 117004, People's Republic of China.
Liu X; School of Pharmacy, Shenyang Pharmaceutical University, 26 Huatuo Road, Benxi, 117004, People's Republic of China.
Song Y; School of Pharmacy, Shenyang Pharmaceutical University, 26 Huatuo Road, Benxi, 117004, People's Republic of China. songyanzhi@syphu.edu.cn.
Deng Y; School of Pharmacy, Shenyang Pharmaceutical University, 26 Huatuo Road, Benxi, 117004, People's Republic of China. dengyihui@syphu.edu.cn.

AAPS PharmSciTech ; 19(7): 3210-3218, 2018 Oct.

Article em En | MEDLINE | ID: mdl-30187444

Assuntos

Polietilenoglicóis/farmacocinética; Animais; Emulsões; Imunoglobulina M/sangue; Injeções Intraperitoneais; Masculino; Nanopartículas; Polietilenoglicóis/administração & dosagem; Ratos; Ratos Wistar; Distribuição Tecidual

Palavras-chave

ABC phenomenon; PEGylated emulsions; anti-PEG IgM; intraperitoneal injection; mast cells

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polietilenoglicóis Tipo de estudo: Evaluation_studies Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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