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Potent α-Synuclein Aggregation Inhibitors, Identified by High-Throughput Screening, Mainly Target the Monomeric State.
Kurnik, Martin; Sahin, Cagla; Andersen, Camilla Bertel; Lorenzen, Nikolai; Giehm, Lise; Mohammad-Beigi, Hossein; Jessen, Christian Moestrup; Pedersen, Jan Skov; Christiansen, Gunna; Petersen, Steen Vang; Staal, Roland; Krishnamurthy, Girija; Pitts, Keith; Reinhart, Peter H; Mulder, Frans A A; Mente, Scot; Hirst, Warren D; Otzen, Daniel E.
Afiliação
  • Kurnik M; iNANO, Aarhus University, Gustav Wieds Vej 14, 8000 Aarhus, Denmark.
  • Sahin C; iNANO, Aarhus University, Gustav Wieds Vej 14, 8000 Aarhus, Denmark; Department of Molecular Biology and Genetics, Aarhus University, Gustav Wieds Vej 10C, 8000 Aarhus, Denmark.
  • Andersen CB; iNANO, Aarhus University, Gustav Wieds Vej 14, 8000 Aarhus, Denmark.
  • Lorenzen N; iNANO, Aarhus University, Gustav Wieds Vej 14, 8000 Aarhus, Denmark.
  • Giehm L; iNANO, Aarhus University, Gustav Wieds Vej 14, 8000 Aarhus, Denmark.
  • Mohammad-Beigi H; iNANO, Aarhus University, Gustav Wieds Vej 14, 8000 Aarhus, Denmark; Biotechnology Group, Faculty of Chemical Engineering, Tarbiat Modares University, P.O. Box 14115-143, Tehran, Iran.
  • Jessen CM; iNANO, Aarhus University, Gustav Wieds Vej 14, 8000 Aarhus, Denmark; Department of Chemistry, Aarhus University, Langelandsgade 140, 8000 Aarhus, Denmark.
  • Pedersen JS; iNANO, Aarhus University, Gustav Wieds Vej 14, 8000 Aarhus, Denmark; Department of Chemistry, Aarhus University, Langelandsgade 140, 8000 Aarhus, Denmark.
  • Christiansen G; Department of Biomedicine, Aarhus University, 8000 Aarhus, Denmark.
  • Petersen SV; Department of Biomedicine, Aarhus University, 8000 Aarhus, Denmark.
  • Staal R; Alentis Pharma, Metuchen, NJ 08840, USA.
  • Krishnamurthy G; Amgen, 360 Binney Street, Cambridge, MA 02141, USA.
  • Pitts K; Genentech, 1 DNA Way, South San Francisco, CA 94080, USA.
  • Reinhart PH; Forma Therapeutics, Inc.Institute for Applied Life Sciences, University of Massachusetts Amherst, 240 Thatcher Road, Amherst, MA 01003-9364, USA.
  • Mulder FAA; iNANO, Aarhus University, Gustav Wieds Vej 14, 8000 Aarhus, Denmark; Department of Chemistry, Aarhus University, Langelandsgade 140, 8000 Aarhus, Denmark.
  • Mente S; Forma Therapeutics, Inc., 500 Arsenal Street, Suite 100, Watertown, MA 02472, USA.
  • Hirst WD; Biogen, 115 Broadway, Cambridge, MA 02142, USA.
  • Otzen DE; iNANO, Aarhus University, Gustav Wieds Vej 14, 8000 Aarhus, Denmark; Department of Molecular Biology and Genetics, Aarhus University, Gustav Wieds Vej 10C, 8000 Aarhus, Denmark. Electronic address: dao@inano.au.dk.
Cell Chem Biol ; 25(11): 1389-1402.e9, 2018 11 15.
Article em En | MEDLINE | ID: mdl-30197194
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Benzoxazóis / Alfa-Sinucleína / Agregados Proteicos / Amiloide Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Benzoxazóis / Alfa-Sinucleína / Agregados Proteicos / Amiloide Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article