A synthetic enzymatic pathway for extremely thermophilic acetone production based on the unexpectedly thermostable acetoacetate decarboxylase from Clostridium acetobutylicum.

Zeldes, Benjamin M; Straub, Christopher T; Otten, Jonathan K; Adams, Michael W W; Kelly, Robert M

Zeldes, Benjamin M; Straub, Christopher T; Otten, Jonathan K; Adams, Michael W W; Kelly, Robert M.

Afiliação

Zeldes BM; Department of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, North Carolina.
Straub CT; Department of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, North Carolina.
Otten JK; Department of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, North Carolina.
Adams MWW; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia.
Kelly RM; Department of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, North Carolina.

Biotechnol Bioeng ; 115(12): 2951-2961, 2018 12.

Article em En | MEDLINE | ID: mdl-30199090

Assuntos

Acetona/metabolismo; Proteínas de Bactérias/metabolismo; Carboxiliases/metabolismo; Clostridium acetobutylicum/enzimologia; Biologia Sintética/métodos; Proteínas de Bactérias/genética; Carboxiliases/genética; Clostridium acetobutylicum/genética; Clostridium acetobutylicum/metabolismo; Estabilidade Enzimática; Temperatura Alta; Engenharia Metabólica; Redes e Vias Metabólicas/genética

Palavras-chave

acetone; biotransformations; extreme thermophiles

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Acetona / Proteínas de Bactérias / Carboxiliases / Clostridium acetobutylicum / Biologia Sintética Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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