[Technical specification for re-evaluation of post-marketing clinical effectiveness of traditional Chinese medicine (first draft)].
Zhongguo Zhong Yao Za Zhi
; 43(15): 3211-3215, 2018 Aug.
Article
em Zh
| MEDLINE
| ID: mdl-30200720
ABSTRACT
The post-marketing re-evaluation of traditional Chinese medicine (TCM) is a crucial stage for drug evaluation. Due to the particularity of TCM, it is necessary to re-evaluate the effectiveness of certain Chinese medicines by studying and collecting the studies on safety of long-term/extensive populations under actual clinical application, in order to verify the effectiveness of post-marketing TCM. However, there is an absence in technical specifications for relevant clinical trials on re-evaluation of effectiveness at present. As a consequence, the preliminary technical specifications were drafted in this article, focusing on several perspectives related to the re-evaluation of post-marketing clinical effectiveness of TCM, including ethical protection, research plan formulation, real-world research methods, randomized controlled trial methods, research methods of clinical pharmacological mechanism, sublimation method of TCM theory and so on. The objective of writing this article is to provide general methodological guidance for the re-evaluation of TCM post-marketing effectiveness, so that the process and results of post-marketing re-evaluation of TCM can be more scientific and reasonable.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Vigilância de Produtos Comercializados
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Projetos de Pesquisa
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Medicamentos de Ervas Chinesas
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Medicina Tradicional Chinesa
Tipo de estudo:
Clinical_trials
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Diagnostic_studies
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Guideline
Limite:
Humans
Idioma:
Zh
Ano de publicação:
2018
Tipo de documento:
Article