Different biological behaviors in left-sided pancreatic cancer according to Yonsei criteria: Proposal of a modified Yonsei criteria score.
Pancreatology
; 18(8): 990-995, 2018 Dec.
Article
em En
| MEDLINE
| ID: mdl-30201440
ABSTRACT
BACKGROUND/OBJECTIVES:
Our institutional experience has demonstrated that bloodless and margin-negative resection is the most potent prognostic factor in treating left-sided pancreatic cancer and we developed selection guideline. The Yonsei criteria (YC) is selection criteria for oncologically safe and effective resection of left-sided pancreatic cancer by a minimally invasive approach. In this study, we investigated whether left-sided pancreatic cancer with YC can be more individualized to predict long-term survival by using clinically and pathologically detectable parameters.METHODS:
From January 2000 to December 2015, 105 patients underwent distal pancreatectomy for left-sided pancreatic cancer. The medical records of the patients were retrospectively reviewed.RESULTS:
Among clinically and pathologically detectable parameters to predict tumor conditions, radiologically determined tumor size (pâ¯=â¯0.080) and SUVmax (pâ¯=â¯0.086) were identified as predictors of early tumor recurrence with marginal significance. Among them, 20% of the patients with YC were identified as having the most favoring tumor condition, with an modified YC score of 3. The patient group with the lowest mYC score was found to have a very long disease-free survival time, with a mean of 108 months, which was statistically different from those with other mYC scores (mYC scoreâ¯=â¯4, mean 47.1 months [95% CI 27.8-69.5] vs. mYC scoreâ¯=â¯5, mean 36.7 months [95% CI 12.7-60.7], vs. mYC scoreâ¯=â¯6, mean 10.7 months [95% CI 3.9-17.4]).CONCLUSIONS:
Modified Yonsei criteria score can predict long-term survival in resected left-sided pancreatic cancer. And patients within YC with a mYC scoreâ¯=â¯3 could have a favorable survival outcome.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Pancreáticas
Tipo de estudo:
Diagnostic_studies
/
Guideline
/
Observational_studies
/
Prognostic_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article