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Conformational heterogeneity of the allosteric drug and metabolite (ADaM) site in AMP-activated protein kinase (AMPK).
Gu, Xin; Bridges, Michael D; Yan, Yan; de Waal, Parker W; Zhou, X Edward; Suino-Powell, Kelly M; Xu, H Eric; Hubbell, Wayne L; Melcher, Karsten.
Afiliação
  • Gu X; From the Center of Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, Michigan 49503.
  • Bridges MD; the Jules Stein Eye Institute and Department of Chemistry and Biochemistry, UCLA School of Medicine, University of California, Los Angeles, California 90095-7008, and.
  • Yan Y; From the Center of Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, Michigan 49503.
  • de Waal PW; the VARI-SIMM Center, Center for Structure and Function of Drug Targets, The CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CAS), Shanghai 201203, China.
  • Zhou XE; From the Center of Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, Michigan 49503.
  • Suino-Powell KM; From the Center of Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, Michigan 49503.
  • Xu HE; From the Center of Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, Michigan 49503.
  • Hubbell WL; From the Center of Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, Michigan 49503.
  • Melcher K; the VARI-SIMM Center, Center for Structure and Function of Drug Targets, The CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CAS), Shanghai 201203, China.
J Biol Chem ; 293(44): 16994-17007, 2018 11 02.
Article em En | MEDLINE | ID: mdl-30206123

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Quinases Ativadas por AMP Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Quinases Ativadas por AMP Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article