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Chemical Instability and Promiscuity of Arylmethylidenepyrazolinone-Based MDMX Inhibitors.
Stefaniak, Jakub; Lewis, Andrew M; Conole, Daniel; Galan, Sébastien R G; Bataille, Carole J R; Wynne, Graham M; Castaldi, M Paola; Lundbäck, Thomas; Russell, Angela J; Huber, Kilian V M.
Afiliação
  • Stefaniak J; Structural Genomics Consortium, Nuffield Department of Medicine , University of Oxford , Oxford , United Kingdom.
  • Lewis AM; Target Discovery Institute, Nuffield Department of Medicine , University of Oxford , Oxford , United Kingdom.
  • Conole D; Department of Chemistry, Chemistry Research Laboratory , University of Oxford , Oxford , United Kingdom.
  • Galan SRG; Structural Genomics Consortium, Nuffield Department of Medicine , University of Oxford , Oxford , United Kingdom.
  • Bataille CJR; Target Discovery Institute, Nuffield Department of Medicine , University of Oxford , Oxford , United Kingdom.
  • Wynne GM; Department of Chemistry, Chemistry Research Laboratory , University of Oxford , Oxford , United Kingdom.
  • Castaldi MP; Department of Chemistry, Chemistry Research Laboratory , University of Oxford , Oxford , United Kingdom.
  • Lundbäck T; Department of Chemistry, Chemistry Research Laboratory , University of Oxford , Oxford , United Kingdom.
  • Russell AJ; Department of Chemistry, Chemistry Research Laboratory , University of Oxford , Oxford , United Kingdom.
  • Huber KVM; Department of Pharmacology , University of Oxford , Oxford , United Kingdom.
ACS Chem Biol ; 13(10): 2849-2854, 2018 10 19.
Article em En | MEDLINE | ID: mdl-30216042
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazóis / Proteínas Nucleares / Proteínas Proto-Oncogênicas / Inibidores Enzimáticos / Acetatos Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazóis / Proteínas Nucleares / Proteínas Proto-Oncogênicas / Inibidores Enzimáticos / Acetatos Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article