Drug-in-mucoadhesive type film for ocular anti-inflammatory potential of amlodipine: Effect of sulphobutyl-ether-beta-cyclodextrin on permeation and molecular docking characterization.

Nanda, Ashirbad; Sahoo, Rudra Narayan; Pramanik, Arunima; Mohapatra, Rajaram; Pradhan, Sukanta Kumar; Thirumurugan, Arun; Das, Debajyoti; Mallick, Subrata

Nanda, Ashirbad; Sahoo, Rudra Narayan; Pramanik, Arunima; Mohapatra, Rajaram; Pradhan, Sukanta Kumar; Thirumurugan, Arun; Das, Debajyoti; Mallick, Subrata.

Afiliação

Nanda A; Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha O Anusandhan, (Deemed to be University), Bhubaneswar, Odisha, India.
Sahoo RN; Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha O Anusandhan, (Deemed to be University), Bhubaneswar, Odisha, India.
Pramanik A; Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha O Anusandhan, (Deemed to be University), Bhubaneswar, Odisha, India.
Mohapatra R; Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha O Anusandhan, (Deemed to be University), Bhubaneswar, Odisha, India.
Pradhan SK; Department of Bioinformatics, Orissa University of Agriculture and Technology, Bhubaneswar, Odisha, India.
Thirumurugan A; Institute of Physics, Bhubaneswar, Odisha, India.
Das D; Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha O Anusandhan, (Deemed to be University), Bhubaneswar, Odisha, India.
Mallick S; Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha O Anusandhan, (Deemed to be University), Bhubaneswar, Odisha, India. Electronic address: profsmallick@gmail.com.

Colloids Surf B Biointerfaces ; 172: 555-564, 2018 Dec 01.

Article em En | MEDLINE | ID: mdl-30218981

Assuntos

Anlodipino/farmacologia; Anti-Inflamatórios/farmacologia; Olho/efeitos dos fármacos; Simulação de Acoplamento Molecular; Muco/química; beta-Ciclodextrinas/química; Adesividade; Anlodipino/química; Animais; Anti-Inflamatórios/química; Varredura Diferencial de Calorimetria; Masculino; Permeabilidade; Coelhos; Ovinos; Espectroscopia de Infravermelho com Transformada de Fourier; Difração de Raios X

Palavras-chave

Amlodipine; Anti-inflammatory activity; Binary and ternary docking; Drug-in-mucoadhesive film; Ocular permeation; Sulphobutyl-ether-beta-cyclodextrin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Anlodipino / Beta-Ciclodextrinas / Olho / Simulação de Acoplamento Molecular / Anti-Inflamatórios / Muco Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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