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ER Stress Drives Lipogenesis and Steatohepatitis via Caspase-2 Activation of S1P.
Kim, Ju Youn; Garcia-Carbonell, Ricard; Yamachika, Shinichiro; Zhao, Peng; Dhar, Debanjan; Loomba, Rohit; Kaufman, Randal J; Saltiel, Alan R; Karin, Michael.
Afiliação
  • Kim JY; Laboratory of Gene Regulation and Signal Transduction, Departments of Pharmacology and Pathology, University of California San Diego, School of Medicine, La Jolla, CA 92093, USA.
  • Garcia-Carbonell R; Laboratory of Gene Regulation and Signal Transduction, Departments of Pharmacology and Pathology, University of California San Diego, School of Medicine, La Jolla, CA 92093, USA.
  • Yamachika S; Laboratory of Gene Regulation and Signal Transduction, Departments of Pharmacology and Pathology, University of California San Diego, School of Medicine, La Jolla, CA 92093, USA.
  • Zhao P; Division of Endocrinology and Metabolism, Department of Medicine, University of California San Diego, School of Medicine, La Jolla, CA 92093, USA.
  • Dhar D; Laboratory of Gene Regulation and Signal Transduction, Departments of Pharmacology and Pathology, University of California San Diego, School of Medicine, La Jolla, CA 92093, USA.
  • Loomba R; NAFLD Research Center, Division of Gastroenterology, University of California San Diego, School of Medicine, La Jolla, CA 92093, USA.
  • Kaufman RJ; Sanford-Burnham-Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Saltiel AR; Division of Endocrinology and Metabolism, Department of Medicine, University of California San Diego, School of Medicine, La Jolla, CA 92093, USA.
  • Karin M; Laboratory of Gene Regulation and Signal Transduction, Departments of Pharmacology and Pathology, University of California San Diego, School of Medicine, La Jolla, CA 92093, USA. Electronic address: karinoffice@ucsd.edu.
Cell ; 175(1): 133-145.e15, 2018 09 20.
Article em En | MEDLINE | ID: mdl-30220454

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Serina Endopeptidases / Pró-Proteína Convertases / Lipogênese / Caspase 2 Limite: Animals / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Serina Endopeptidases / Pró-Proteína Convertases / Lipogênese / Caspase 2 Limite: Animals / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article