A DNA nick at Ku-blocked double-strand break ends serves as an entry site for exonuclease 1 (Exo1) or Sgs1-Dna2 in long-range DNA end resection.

Wang, Weibin; Daley, James M; Kwon, Youngho; Xue, Xiaoyu; Krasner, Danielle S; Miller, Adam S; Nguyen, Kevin A; Williamson, Elizabeth A; Shim, Eun Yong; Lee, Sang Eun; Hromas, Robert; Sung, Patrick

Wang, Weibin; Daley, James M; Kwon, Youngho; Xue, Xiaoyu; Krasner, Danielle S; Miller, Adam S; Nguyen, Kevin A; Williamson, Elizabeth A; Shim, Eun Yong; Lee, Sang Eun; Hromas, Robert; Sung, Patrick.

Afiliação

Wang W; From the Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, Connecticut 06520 and.
Daley JM; From the Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, Connecticut 06520 and.
Kwon Y; From the Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, Connecticut 06520 and.
Xue X; Departments of Biochemistry and Structural Biology.
Krasner DS; From the Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, Connecticut 06520 and.
Miller AS; From the Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, Connecticut 06520 and.
Nguyen KA; From the Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, Connecticut 06520 and.
Williamson EA; From the Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, Connecticut 06520 and.
Shim EY; Medicine.
Lee SE; Radiation Oncology, and.
Hromas R; Radiation Oncology, and.
Sung P; Molecular Medicine, University of Texas Health Science Center, San Antonio, Texas 78229.

J Biol Chem ; 293(44): 17061-17069, 2018 11 02.

Article em En | MEDLINE | ID: mdl-30224356

Assuntos

Quebras de DNA de Cadeia Dupla; DNA Helicases/metabolismo; Proteínas de Ligação a DNA/metabolismo; Exodesoxirribonucleases/metabolismo; RecQ Helicases/metabolismo; Proteína de Replicação A/metabolismo; Proteínas de Saccharomyces cerevisiae/metabolismo; Saccharomyces cerevisiae/genética; DNA Helicases/genética; Reparo do DNA; Proteínas de Ligação a DNA/genética; Exodesoxirribonucleases/genética; Recombinação Homóloga; RecQ Helicases/genética; Proteína de Replicação A/genética; Saccharomyces cerevisiae/enzimologia; Saccharomyces cerevisiae/metabolismo; Proteínas de Saccharomyces cerevisiae/genética

Palavras-chave

DNA binding protein; DNA damage; DNA end resection; DNA gap; DNA helicase; DNA nick; DNA repair; Exo1; Sgs1-Dna2; homologous recombination; nuclease

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Saccharomyces cerevisiae / DNA Helicases / Proteínas de Saccharomyces cerevisiae / Proteínas de Ligação a DNA / Proteína de Replicação A / Exodesoxirribonucleases / RecQ Helicases / Quebras de DNA de Cadeia Dupla Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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