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Low In Vitro Antifungal Activity of Tavaborole against Yeasts and Molds from Onychomycosis.
Abastabar, Mahdi; Haghani, Iman; Shokohi, Tahereh; Hedayati, Mohammad Taghi; Aghili, Seyed Reza; Jedi, Ali; Dadashi, Sulmaz; Shabanzadeh, Shafigheh; Hosseini, Tahereh; Aslani, Narges; Meis, Jacques F; Badali, Hamid.
Afiliação
  • Abastabar M; Invasive Fungi Research Center (IFRC), School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
  • Haghani I; Invasive Fungi Research Center (IFRC), School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
  • Shokohi T; Invasive Fungi Research Center (IFRC), School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
  • Hedayati MT; Invasive Fungi Research Center (IFRC), School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
  • Aghili SR; Invasive Fungi Research Center (IFRC), School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
  • Jedi A; Student Research Committee, Mazandaran University of Medical Sciences, Sari, Iran.
  • Dadashi S; Student Research Committee, Mazandaran University of Medical Sciences, Sari, Iran.
  • Shabanzadeh S; Invasive Fungi Research Center (IFRC), School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
  • Hosseini T; Student Research Committee, Mazandaran University of Medical Sciences, Sari, Iran.
  • Aslani N; Department of Medical Parasitology and Mycology, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran.
  • Meis JF; Centre of Expertise in Mycology Radboud University Medical Centre/Canisius Wilhelmina Hospital, Nijmegen, The Netherlands.
  • Badali H; Department of Medical Microbiology and Infectious Diseases, Canisius Wilhelmina Hospital, Nijmegen, The Netherlands.
Antimicrob Agents Chemother ; 62(12)2018 12.
Article em En | MEDLINE | ID: mdl-30224524
ABSTRACT
The in vitro activity of tavaborole, an FDA-approved antifungal drug, was compared to that of four antifungal agents against 170 clinical fungal isolates originating from patients with onychomycosis. Tavaborole had low activity against all isolates compared to itraconazole, terbinafine, and fluconazole, the principal choices for treatment of onychomycosis. Thus, it appears that tavaborole is not a candidate for the treatment of onychomycosis due to Candida species, Aspergillus species, and dermatophytes.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leveduras / Compostos de Boro / Onicomicose / Compostos Bicíclicos Heterocíclicos com Pontes / Fungos / Antifúngicos Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leveduras / Compostos de Boro / Onicomicose / Compostos Bicíclicos Heterocíclicos com Pontes / Fungos / Antifúngicos Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article