Your browser doesn't support javascript.
loading
Assessment of patient-reported outcomes (PROs): treatment satisfaction, medication adherence, and quality of life (QoL) and the associated factors in postmenopausal osteoporosis (PMO) patients in Korea.
Byun, Dong Won; Moon, Seong-Hwan; Kim, Tak; Lee, Hae-Hyeog; Park, Hyoung Moo; Kang, Moo-Il; Ha, Yong-Chan; Chung, Ho-Yeon; Yoon, Byung-Koo; Kim, Tae-Young; Chae, Soo Uk; Shin, Chan Soo; Yang, Kyu-Hyun; Lee, Jae Hyup; Chang, Jae Suk; Kim, Sung Hoon; Kim, In Joo; Koh, Jung-Min; Jung, Jung Hwa; Yi, Kyong Wook; Yoo, Jeong Joon; Chung, Dong Jin; Lee, Young-Kyun; Yoon, Hyun-Koo; Hong, Seongbin; Kim, Deog-Yoon; Baek, Ki Hyun; Kim, Hyun-Joo; Kim, Young-Joo; Kang, Seongsik; Min, Yong-Ki.
Afiliação
  • Byun DW; Department of Endocrinology, Internal Medicine, Soon Chun Hyang University Hospital, Seoul, South Korea.
  • Moon SH; Department of Orthopedic Surgery, Severance Hospital, Yonsei University Health System, Seoul, South Korea.
  • Kim T; Department of Obstetrics and Gynecology, Korea University Anam Hospital, Korea University College of Medicine, Seoul, South Korea.
  • Lee HH; Department of Obstetrics and Gynecology, Soonchunhyang University Bucheon Hospital, Bucheon, South Korea.
  • Park HM; Department of Obstetrics and Gynecology, Chung-Ang University Hospital, Seoul, South Korea.
  • Kang MI; Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul St. Mary's Hospital, Seoul, South Korea.
  • Ha YC; Department of Orthopedic Surgery, Chung-Ang University Hospital, Seoul, South Korea.
  • Chung HY; Department of Endocrinology and Metabolism, Kyung Hee University, School of Medicine, Seoul, South Korea.
  • Yoon BK; Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University, Seoul, South Korea.
  • Kim TY; Department of Orthopedic Surgery, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, South Korea.
  • Chae SU; Department of Orthopedic Surgery, Gunsan Medical Center of Wonkwang University Hospital, Gunsan, South Korea.
  • Shin CS; Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea.
  • Yang KH; Department of Orthopedic Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea.
  • Lee JH; Department of Orthopedic Surgery, Seoul National University College of Medicine, SMG-SNU Boramae Medical Center, Seoul, South Korea.
  • Chang JS; Department of Orthopedic Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
  • Kim SH; Department of Obstetrics and Gynecology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
  • Kim IJ; Division of Endocrinology and Metabolism, Department of Internal Medicine, Pusan National University Hospital, Busan, South Korea.
  • Koh JM; Division of Endocrinology and Metabolism, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
  • Jung JH; Department of Internal Medicine, Gyeongsang National University Hospital, Gyeongsang National University School of Medicine, Jinju, South Korea.
  • Yi KW; Department of Obstetrics and Gynecology, Korea University College of Medicine, Korea University Ansan Hospital, Ansan, South Korea.
  • Yoo JJ; Department of Orthopedic Surgery, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, South Korea.
  • Chung DJ; Department of Internal Medicine, Chonnam National University Medical School, Gwangju, South Korea.
  • Lee YK; Department of Orthopedic Surgery, Seoul National University Bundang Hospital, Seongnam, South Korea.
  • Yoon HK; Division of Endocrinology and Metabolism, Department of Medicine, Cheil General Hospital and Women's Healthcare Center, Dankook University, Seoul, South Korea.
  • Hong S; Division of Endocrinology and Metabolism, Department of Internal Medicine, Inha University Hospital, Inha University School of Medicine, Incheon, South Korea.
  • Kim DY; Department of Nuclear Medicine, Kyung Hee University, School of Medicine, Seoul, South Korea.
  • Baek KH; Division of Endocrinology and Metabolism, Department of Internal Medicine, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
  • Kim HJ; Pfizer Pharmaceuticals Korea Limited, Seoul, Republic of Korea.
  • Kim YJ; Pfizer Pharmaceuticals Korea Limited, Seoul, Republic of Korea.
  • Kang S; Pfizer Pharmaceuticals Korea Limited, Seoul, Republic of Korea.
  • Min YK; Division of Endocrinology and Metabolism, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. ykmin@skku.edu.
J Bone Miner Metab ; 37(3): 563-572, 2019 May.
Article em En | MEDLINE | ID: mdl-30238428
Patient-reported outcomes (PROs) provide practical guides for treatment; however, studies that have evaluated PROs of women in Korea with postmenopausal osteoporosis (PMO) are lacking. This cross-sectional, multi-center (29 nationwide hospitals) study, performed from March 2013 to July 2014, aimed to assess PROs related to treatment satisfaction, medication adherence, and quality of life (QoL) in Korean PMO women using osteoporosis medication for prevention/treatment. Patient demographics, clinical characteristics, treatment patterns, PROs, and experience using medication were collected. The 14-item Treatment Satisfaction Questionnaire for Medication (TSQM) (score-range, 0-100; domains: effectiveness, side effects, convenience, global satisfaction), Osteoporosis-Specific Morisky Medication Adherence Scale (OS-MMAS) (score-range, 0-8), and EuroQol-5 dimensions questionnaire (index score range, - 0.22 to 1.0; EuroQol visual analog scale score range, 0-100) were used. To investigate factors associated with PROs, linear (treatment satisfaction/QoL) or logistic (medication adherence) regression analyses were conducted. A total of 1804 patients (age, 62 years) were investigated; 60.1% used bisphosphonate, with the majority (67.2%) using weekly medication, 27.8% used daily hormone replacement therapy, and 12.1% used daily selective estrogen receptor modulator. Several patients reported gastrointestinal (GI) events (31.6%) and dental visits due to problems (24.1%) while using medication. Factors associated with the highest OS-MMAS domain scores were convenience and global satisfaction. GI events were associated with non-adherence. TSQM scores for effectiveness, side effects, and GI risk factors were significantly associated with QoL. Our study elaborately assessed the factors associated with PROs of Korean PMO women. Based on our findings, appropriate treatment-related adjustments such as frequency/choice of medications and GI risk management may improve PROs.
Assuntos
Palavras-chave

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Qualidade de Vida / Osteoporose Pós-Menopausa / Satisfação do Paciente / Adesão à Medicação / Medidas de Resultados Relatados pelo Paciente Tipo de estudo: Clinical_trials / Observational_studies / Prevalence_studies / Qualitative_research / Risk_factors_studies Limite: Female / Humans / Middle aged País/Região como assunto: Asia Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Qualidade de Vida / Osteoporose Pós-Menopausa / Satisfação do Paciente / Adesão à Medicação / Medidas de Resultados Relatados pelo Paciente Tipo de estudo: Clinical_trials / Observational_studies / Prevalence_studies / Qualitative_research / Risk_factors_studies Limite: Female / Humans / Middle aged País/Região como assunto: Asia Idioma: En Ano de publicação: 2019 Tipo de documento: Article