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Association Between High Levels of Hepatitis B Core Antibody and Seroclearance of Hepatitis B e Antigen in Individuals With Chronic Hepatitis B Virus Infection.
Liu, Jessica; Hu, Hui-Han; Chang, Chia-Ling; Jen, Chin-Lan; Lee, Mei-Hsuan; Lu, Sheng-Nan; Wang, Li-Yu; Yuan, Quan; Xia, Ning-Shao; Sugiyama, Masaya; Nishida, Nao; Mizokami, Masashi; Chen, Chien-Jen; Chen, Pei-Jer; Yang, Hwai-I.
Afiliação
  • Liu J; Genomics Research Center, Academia Sinica, Taipei, Taiwan.
  • Hu HH; Genomics Research Center, Academia Sinica, Taipei, Taiwan.
  • Chang CL; Genomics Research Center, Academia Sinica, Taipei, Taiwan.
  • Jen CL; Genomics Research Center, Academia Sinica, Taipei, Taiwan.
  • Lee MH; Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan.
  • Lu SN; Department of Gastroenterology, Chang-Gung Memorial Hospital, Kaohsiung, Taiwan.
  • Wang LY; MacKay College of Medicine, New Taipei City, Taiwan.
  • Yuan Q; School of Public Health, Xiamen University, Xiamen, Fujian, China.
  • Xia NS; School of Public Health, Xiamen University, Xiamen, Fujian, China.
  • Sugiyama M; The Research Center for Hepatitis and Immunology, National Center for Global Health and Medicine, Ichikawa, Japan.
  • Nishida N; The Research Center for Hepatitis and Immunology, National Center for Global Health and Medicine, Ichikawa, Japan.
  • Mizokami M; The Research Center for Hepatitis and Immunology, National Center for Global Health and Medicine, Ichikawa, Japan; Department of Hepatitis and Immunology, Nagoya City University Graduate School of Medical Science, Nagoya, Japan.
  • Chen CJ; Academia Sinica, Taipei, Taiwan.
  • Chen PJ; Division of Gastroenterology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan; Graduate Institute of Clinical Medicine, National Taiwan University, Taipei, Taiwan.
  • Yang HI; Genomics Research Center, Academia Sinica, Taipei, Taiwan; Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan. Electronic address: hiyang@gate.sinica.edu.tw.
Clin Gastroenterol Hepatol ; 17(7): 1413-1415, 2019 06.
Article em En | MEDLINE | ID: mdl-30267868
ABSTRACT
For chronic hepatitis B patients, hepatitis B e antigen (HBeAg) seroclearance signals a transition from an immunologically active phase to an inactive carrier state with a reduction in hepatitis B virus (HBV) DNA levels and a reduced risk of hepatocellular carcinoma (HCC).1 Predictors of HBeAg seroclearance include lower HBV DNA levels, viral genotype, the precore mutation, and higher serum alanine aminotransferase (ALT) levels.2.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vírus da Hepatite B / Carga Viral / Hepatite B Crônica / Anticorpos Anti-Hepatite B / Antígenos de Superfície da Hepatite B Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vírus da Hepatite B / Carga Viral / Hepatite B Crônica / Anticorpos Anti-Hepatite B / Antígenos de Superfície da Hepatite B Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article