IL-6 augments IL-4-induced polarization of primary human macrophages through synergy of STAT3, STAT6 and BATF transcription factors.

Gupta, Sahil; Jain, Arpit; Syed, Shahzad Nawaz; Snodgrass, Ryan G; Pflüger-Müller, Beatrice; Leisegang, Matthias S; Weigert, Andreas; Brandes, Ralf P; Ebersberger, Ingo; Brüne, Bernhard; Namgaladze, Dmitry

Gupta, Sahil; Jain, Arpit; Syed, Shahzad Nawaz; Snodgrass, Ryan G; Pflüger-Müller, Beatrice; Leisegang, Matthias S; Weigert, Andreas; Brandes, Ralf P; Ebersberger, Ingo; Brüne, Bernhard; Namgaladze, Dmitry.

Afiliação

Gupta S; Faculty of Medicine, Institute of Biochemistry I, Goethe-University Frankfurt, Frankfurt, Germany.
Jain A; Department for Applied Bioinformatics, Institute for Cell Biology and Neuroscience, Goethe-University Frankfurt, Frankfurt, Germany.
Syed SN; Faculty of Medicine, Institute of Biochemistry I, Goethe-University Frankfurt, Frankfurt, Germany.
Snodgrass RG; Faculty of Medicine, Institute of Biochemistry I, Goethe-University Frankfurt, Frankfurt, Germany.
Pflüger-Müller B; Faculty of Medicine, Institute for Cardiovascular Physiology, Goethe-University Frankfurt, Frankfurt, Germany.
Leisegang MS; German Center of Cardiovascular Research (DZHK), Partner Site Rhein-Main, Frankfurt, Germany.
Weigert A; Faculty of Medicine, Institute for Cardiovascular Physiology, Goethe-University Frankfurt, Frankfurt, Germany.
Brandes RP; German Center of Cardiovascular Research (DZHK), Partner Site Rhein-Main, Frankfurt, Germany.
Ebersberger I; Faculty of Medicine, Institute of Biochemistry I, Goethe-University Frankfurt, Frankfurt, Germany.
Brüne B; Faculty of Medicine, Institute for Cardiovascular Physiology, Goethe-University Frankfurt, Frankfurt, Germany.
Namgaladze D; German Center of Cardiovascular Research (DZHK), Partner Site Rhein-Main, Frankfurt, Germany.

Oncoimmunology ; 7(10): e1494110, 2018.

Article em En | MEDLINE | ID: mdl-30288360

Palavras-chave

CRISPR interference (CRISPRi); RNA sequencing; basic leucine zipper ATF-like transcription factor (BATF); interleukins; primary human monocyte derived macrophages (hMDMs); signal transducer and activator of transcription (STAT)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2018 Tipo de documento: Article