The Sign of Leser-Trelát and Malignant Acanthosis Nigricans Associated With Fallopian Tube Carcinoma.
Obstet Gynecol
; 132(5): 1116-1119, 2018 11.
Article
em En
| MEDLINE
| ID: mdl-30303917
ABSTRACT
BACKGROUND:
The sign of Leser-Trelát is controversial and rarely reported in gynecologic malignancies. It is characterized by rapid development of new or enlarging seborrheic keratoses. CASE A 78-year-old woman presented with unintentional weight loss and new-onset erythematous patches and plaques with thickened, rugated skin and stuck-on brown waxy papules on the chest and back. Her symptoms were concerning for a paraneoplastic eruption; workup revealed an elevated CA 125 level and an ovarian mass on abdominal computed tomography scan. Exploratory laparotomy revealed a stage IIIC serous fallopian tube carcinoma and a synchronous low-grade endometrioid adenocarcinoma of the endometrium.CONCLUSION:
The sign of Leser-Trelát can be associated with fallopian tube carcinoma. When recognized, paraneoplastic dermatoses can prompt clinicians to initiate a workup for occult malignancy.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Síndromes Paraneoplásicas
/
Adenocarcinoma
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Neoplasias do Endométrio
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Ceratose Seborreica
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Neoplasias Císticas, Mucinosas e Serosas
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Neoplasias das Tubas Uterinas
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Acantose Nigricans
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Neoplasias Primárias Múltiplas
Tipo de estudo:
Diagnostic_studies
/
Risk_factors_studies
Limite:
Aged
/
Female
/
Humans
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article