Proof of concept in utilizing in-trans surface display system of Lactobacillus plantarum as mucosal tuberculosis vaccine via oral administration in mice.

Mustafa, Anhar Danial; Kalyanasundram, Jeevanathan; Sabidi, Sarah; Song, Adelene Ai-Lian; Abdullah, Maha; Abdul Rahim, Raha; Yusoff, Khatijah

Mustafa, Anhar Danial; Kalyanasundram, Jeevanathan; Sabidi, Sarah; Song, Adelene Ai-Lian; Abdullah, Maha; Abdul Rahim, Raha; Yusoff, Khatijah.

Afiliação

Mustafa AD; Department of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences Universiti Putra Malaysia, 43400, Serdang, Selangor Darul Ehsan, Malaysia.
Kalyanasundram J; Department of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences Universiti Putra Malaysia, 43400, Serdang, Selangor Darul Ehsan, Malaysia.
Sabidi S; Department of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences Universiti Putra Malaysia, 43400, Serdang, Selangor Darul Ehsan, Malaysia.
Song AA; Department of Microbiology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor Darul Ehsan, Malaysia.
Abdullah M; Department of Pathology, Faculty of Medicine and Health Science, Universiti Putra Malaysia, 43400, Serdang, Selangor Darul Ehsan, Malaysia.
Abdul Rahim R; Department of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences Universiti Putra Malaysia, 43400, Serdang, Selangor Darul Ehsan, Malaysia.
Yusoff K; Institute of Bioscience, Universiti Putra Malaysia, 43400, Serdang, Selangor Darul Ehsan, Malaysia.

BMC Biotechnol ; 18(1): 63, 2018 10 11.

Article em En | MEDLINE | ID: mdl-30309359

Assuntos

Lactobacillus plantarum/genética; Vacinas contra a Tuberculose/administração & dosagem; Vacinas contra a Tuberculose/genética; Tuberculose/prevenção & controle; Aciltransferases/administração & dosagem; Aciltransferases/genética; Aciltransferases/imunologia; Administração Oral; Animais; Antígenos de Bactérias/administração & dosagem; Antígenos de Bactérias/genética; Antígenos de Bactérias/imunologia; Proteínas de Bactérias/administração & dosagem; Proteínas de Bactérias/genética; Proteínas de Bactérias/imunologia; Feminino; Expressão Gênica; Humanos; Imunização; Interleucina-2/genética; Interleucina-2/imunologia; Interleucina-4/genética; Interleucina-4/imunologia; Interleucina-6/genética; Interleucina-6/imunologia; Lactobacillus plantarum/metabolismo; Camundongos; Camundongos Endogâmicos BALB C; Mycobacterium tuberculosis/genética; Mycobacterium tuberculosis/imunologia; Tuberculose/genética; Tuberculose/imunologia; Tuberculose/microbiologia; Vacinas contra a Tuberculose/imunologia

Palavras-chave

In-trans approach; L. plantarum; M. tuberculosis vaccine; Surface display vaccine

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tuberculose / Vacinas contra a Tuberculose / Lactobacillus plantarum Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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