Differential Effects of Autophagy-Related 10 Protein on HCV Replication and Autophagy Flux Are Mediated by Its Cysteine<sup>44</sup> and Cysteine<sup>135</sup>.

Zhang, Miao-Qing; Li, Jian-Rui; Peng, Zong-Gen; Zhang, Jing-Pu

Differential Effects of Autophagy-Related 10 Protein on HCV Replication and Autophagy Flux Are Mediated by Its Cysteine⁴⁴ and Cysteine¹³⁵.

Zhang, Miao-Qing; Li, Jian-Rui; Peng, Zong-Gen; Zhang, Jing-Pu.

Afiliação

Zhang MQ; Key Laboratory of Biotechnology of Antibiotics, National Health Commission (NHC), Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Li JR; Key Laboratory of Biotechnology of Antibiotics, National Health Commission (NHC), Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Peng ZG; Key Laboratory of Biotechnology of Antibiotics, National Health Commission (NHC), Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Zhang JP; Key Laboratory of Biotechnology of Antibiotics, National Health Commission (NHC), Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Front Immunol ; 9: 2176, 2018.

Article em En | MEDLINE | ID: mdl-30319633

Assuntos

Proteínas Relacionadas à Autofagia/imunologia; Autofagia/imunologia; Hepacivirus/fisiologia; Proteínas de Transporte Vesicular/imunologia; Replicação Viral/imunologia; Substituição de Aminoácidos; Autofagia/genética; Proteínas Relacionadas à Autofagia/genética; Cisteína/genética; Cisteína/imunologia; Células Hep G2; Humanos; Mutação de Sentido Incorreto; Proteínas de Transporte Vesicular/genética; Replicação Viral/genética

Palavras-chave

ATG10; HCV subgenomic replicon; IL28A; autophagy flux; cysteine; disulfide bond; lysosomal degradation; structure-function relationship

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autofagia / Replicação Viral / Hepacivirus / Proteínas de Transporte Vesicular / Proteínas Relacionadas à Autofagia Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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