Elevated levels of platelet- and red cell-derived extracellular vesicles in transfusion-dependent ß-thalassemia/HbE patients with pulmonary arterial hypertension.

Manakeng, Kanchana; Prasertphol, Phongsak; Phongpao, Kunwadee; Chuncharunee, Suporn; Tanyong, Dalina; Worawichawong, Suchin; Svasti, Saovaros; Chaichompoo, Pornthip

Manakeng, Kanchana; Prasertphol, Phongsak; Phongpao, Kunwadee; Chuncharunee, Suporn; Tanyong, Dalina; Worawichawong, Suchin; Svasti, Saovaros; Chaichompoo, Pornthip.

Afiliação

Manakeng K; Department of Clinical Microscopy, Faculty of Medical Technology, Mahidol University, Bangkok, Thailand.
Prasertphol P; Thalassemia Research Center, Institute of Molecular Biosciences, Mahidol University, Nakhon Pathom, Thailand.
Phongpao K; Electron Microscopy Unit, Department of Pathology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Chuncharunee S; Thalassemia Research Center, Institute of Molecular Biosciences, Mahidol University, Nakhon Pathom, Thailand.
Tanyong D; Division of Hematology, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Worawichawong S; Department of Clinical Microscopy, Faculty of Medical Technology, Mahidol University, Bangkok, Thailand.
Svasti S; Electron Microscopy Unit, Department of Pathology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Chaichompoo P; Thalassemia Research Center, Institute of Molecular Biosciences, Mahidol University, Nakhon Pathom, Thailand.

Ann Hematol ; 98(2): 281-288, 2019 Feb.

Article em En | MEDLINE | ID: mdl-30334069

Assuntos

Plaquetas; Micropartículas Derivadas de Células/metabolismo; Eritrócitos; Hipertensão Pulmonar/sangue; Talassemia beta/sangue; Adulto; Biomarcadores/sangue; Transfusão de Sangue; Feminino; Hemoglobina E; Humanos; Hipertensão Pulmonar/etiologia; Hipertensão Pulmonar/terapia; Masculino; Pessoa de Meia-Idade; Ativação Plaquetária; Esplenectomia; Talassemia beta/complicações; Talassemia beta/terapia

Palavras-chave

Antiplatelet; Beta-thalassemia; Extracellular vesicles; Hypercoagulable state; Pulmonary arterial hypertension

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Plaquetas / Talassemia beta / Eritrócitos / Micropartículas Derivadas de Células / Hipertensão Pulmonar Tipo de estudo: Clinical_trials / Etiology_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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