Different ST2 Serum Concentrations in Asymptomatic and Symptomatic Carotid Artery Stenosis.
Ann Vasc Surg
; 56: 240-245, 2019 Apr.
Article
em En
| MEDLINE
| ID: mdl-30339898
ABSTRACT
BACKGROUND:
ST2 represents an interesting biomarker associated with the progression of atherosclerotic disease.METHODS:
This study aims to detect different ST2 serum concentrations, and intraplaque ST2 expression, in patients with symptomatic and asymptomatic carotid artery stenosis.RESULTS:
The analysis of ST2 expression in the atheromatous plaque did not show any significant difference between symptomatic and asymptomatic patients (39.61 ± 35.97 vs. 38.49 ± 35.26; P = ns). ST2 serum concentrations of asymptomatic and symptomatic patients were statistically different with a concentration of 11.04 ± 8.95 ng/mL and 13.91 ± 8.01 ng/mL, respectively (P = 0.037). We observed statistical difference in serum ST2 levels between asymptomatic and symptomatic patients for cerebrovascular acute disease. No differences have been obtained in intraplaque ST2 expression.CONCLUSIONS:
Soluble serum ST2 levels can be a useful biomarker to identify patients at risk for cerebrovascular events.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transtornos Cerebrovasculares
/
Estenose das Carótidas
/
Proteína 1 Semelhante a Receptor de Interleucina-1
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Aged
/
Female
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article