Biosynthetic study of conidiation-inducing factor conidiogenone: heterologous production and cyclization mechanism of a key bifunctional diterpene synthase.

Shiina, Tetsuya; Nakagawa, Kazuya; Fujisaki, Yukiko; Ozaki, Taro; Liu, Chengwei; Toyomasu, Tomonobu; Hashimoto, Masaru; Koshino, Hiroyuki; Minami, Atsushi; Kawaide, Hiroshi; Oikawa, Hideaki

Shiina, Tetsuya; Nakagawa, Kazuya; Fujisaki, Yukiko; Ozaki, Taro; Liu, Chengwei; Toyomasu, Tomonobu; Hashimoto, Masaru; Koshino, Hiroyuki; Minami, Atsushi; Kawaide, Hiroshi; Oikawa, Hideaki.

Afiliação

Shiina T; a Department of Chemistry, Faculty of Science , Hokkaido University , Sapporo , Japan.
Nakagawa K; b Institute of Agriculture , Tokyo University of Agriculture and Technology , Fuchu , Japan.
Fujisaki Y; c Department of Agriculture , Yamagata University , Tsuruoka , Japan.
Ozaki T; a Department of Chemistry, Faculty of Science , Hokkaido University , Sapporo , Japan.
Liu C; a Department of Chemistry, Faculty of Science , Hokkaido University , Sapporo , Japan.
Toyomasu T; c Department of Agriculture , Yamagata University , Tsuruoka , Japan.
Hashimoto M; d Faculty of Agriculture and Life Science , Hirosaki University , Hirosaki , Japan.
Koshino H; e Center for Sustainable Resource Science , RIKEN , Wako-shi , Japan.
Minami A; a Department of Chemistry, Faculty of Science , Hokkaido University , Sapporo , Japan.
Kawaide H; b Institute of Agriculture , Tokyo University of Agriculture and Technology , Fuchu , Japan.
Oikawa H; a Department of Chemistry, Faculty of Science , Hokkaido University , Sapporo , Japan.

Biosci Biotechnol Biochem ; 83(2): 192-201, 2019 Feb.

Article em En | MEDLINE | ID: mdl-30343633

Assuntos

Alquil e Aril Transferases/metabolismo; Diterpenos/metabolismo; Alquil e Aril Transferases/genética; Aspergillus oryzae/genética; Espectroscopia de Ressonância Magnética Nuclear de Carbono-13; Clonagem Molecular; Ciclização; DNA Complementar/genética; Teoria da Densidade Funcional; Diterpenos/química; Genes Fúngicos; Espectrometria de Massas; Modelos Moleculares; Estrutura Molecular; Penicillium/enzimologia; Penicillium/genética; Espectroscopia de Prótons por Ressonância Magnética

Palavras-chave

Biosynthesis; NMR analysis; conidiogenone; diterpene

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Alquil e Aril Transferases / Diterpenos Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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