Ex vivo human HSC expansion requires coordination of cellular reprogramming with mitochondrial remodeling and p53 activation.

Papa, Luena; Zimran, Eran; Djedaini, Mansour; Ge, Yongchao; Ozbek, Umut; Sebra, Robert; Sealfon, Stuart C; Hoffman, Ronald

Papa, Luena; Zimran, Eran; Djedaini, Mansour; Ge, Yongchao; Ozbek, Umut; Sebra, Robert; Sealfon, Stuart C; Hoffman, Ronald.

Afiliação

Papa L; Division of Hematology/Oncology, Tisch Cancer Institute.
Zimran E; Division of Hematology/Oncology, Tisch Cancer Institute.
Djedaini M; Division of Hematology/Oncology, Tisch Cancer Institute.
Ge Y; Department of Neurology, and.
Ozbek U; Division of Hematology/Oncology, Tisch Cancer Institute.
Sebra R; Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY.
Sealfon SC; Department of Neurology, and.
Hoffman R; Division of Hematology/Oncology, Tisch Cancer Institute.

Blood Adv ; 2(20): 2766-2779, 2018 10 23.

Article em En | MEDLINE | ID: mdl-30348672

Assuntos

Reprogramação Celular/genética; Células-Tronco Hematopoéticas/metabolismo; Mitocôndrias/metabolismo; Proteína Supressora de Tumor p53/metabolismo; Células-Tronco Hematopoéticas/citologia; Humanos

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Hematopoéticas / Proteína Supressora de Tumor p53 / Reprogramação Celular / Mitocôndrias Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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