Tetrachlorobenzoquinone-Induced Nrf2 Confers Neuron-like PC12 Cells Resistance to Endoplasmic Reticulum Stress via Regulating Glutathione Synthesis and Protein Thiol Homeostasis.

Liu, Zixuan; Dong, Wenjing; Yang, Bingwei; Peng, Lu; Xia, Xiaomin; Pu, Lanxiang; Zhang, Na; Song, Erqun; Song, Yang

Liu, Zixuan; Dong, Wenjing; Yang, Bingwei; Peng, Lu; Xia, Xiaomin; Pu, Lanxiang; Zhang, Na; Song, Erqun; Song, Yang.

Afiliação

Liu Z; Key Laboratory of Luminescence and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Pharmaceutical Sciences , Southwest University , Chongqing , People's Republic of China , 400715.
Dong W; Key Laboratory of Luminescence and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Pharmaceutical Sciences , Southwest University , Chongqing , People's Republic of China , 400715.
Yang B; Key Laboratory of Luminescence and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Pharmaceutical Sciences , Southwest University , Chongqing , People's Republic of China , 400715.
Peng L; Key Laboratory of Luminescence and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Pharmaceutical Sciences , Southwest University , Chongqing , People's Republic of China , 400715.
Xia X; Key Laboratory of Luminescence and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Pharmaceutical Sciences , Southwest University , Chongqing , People's Republic of China , 400715.
Pu L; Key Laboratory of Luminescence and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Pharmaceutical Sciences , Southwest University , Chongqing , People's Republic of China , 400715.
Zhang N; Key Laboratory of Luminescence and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Pharmaceutical Sciences , Southwest University , Chongqing , People's Republic of China , 400715.
Song E; Key Laboratory of Luminescence and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Pharmaceutical Sciences , Southwest University , Chongqing , People's Republic of China , 400715.
Song Y; Key Laboratory of Luminescence and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Pharmaceutical Sciences , Southwest University , Chongqing , People's Republic of China , 400715.

Chem Res Toxicol ; 31(11): 1230-1239, 2018 11 19.

Article em En | MEDLINE | ID: mdl-30358983

Assuntos

Benzoquinonas/toxicidade; Estresse do Retículo Endoplasmático/efeitos dos fármacos; Glutationa/metabolismo; Hidrocarbonetos Clorados/toxicidade; Fator 2 Relacionado a NF-E2/metabolismo; Compostos de Sulfidrila/metabolismo; Sistema y+ de Transporte de Aminoácidos/metabolismo; Animais; Apoptose/efeitos dos fármacos; Sobrevivência Celular/efeitos dos fármacos; Glutamato-Cisteína Ligase/metabolismo; Fator 2 Relacionado a NF-E2/antagonistas & inibidores; Fator 2 Relacionado a NF-E2/genética; Neurônios/citologia; Neurônios/efeitos dos fármacos; Neurônios/metabolismo; Células PC12; Interferência de RNA; RNA Interferente Pequeno/metabolismo; Ratos

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos de Sulfidrila / Benzoquinonas / Fator 2 Relacionado a NF-E2 / Estresse do Retículo Endoplasmático / Glutationa / Hidrocarbonetos Clorados Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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