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Linking the Gastrointestinal Behavior of Ibuprofen with the Systemic Exposure between and within Humans-Part 1: Fasted State Conditions.
Bermejo, Marival; Paixão, Paulo; Hens, Bart; Tsume, Yasuhiro; Koenigsknecht, Mark J; Baker, Jason R; Hasler, William L; Lionberger, Robert; Fan, Jianghong; Dickens, Joseph; Shedden, Kerby; Wen, Bo; Wysocki, Jeffrey; Löbenberg, Raimar; Lee, Allen; Frances, Ann; Amidon, Gregory E; Yu, Alex; Salehi, Niloufar; Talattof, Arjang; Benninghoff, Gail; Sun, Duxin; Kuminek, Gislaine; Cavanagh, Katie L; Rodríguez-Hornedo, Naír; Amidon, Gordon L.
Afiliação
  • Bermejo M; Department of Pharmaceutical Sciences, College of Pharmacy , University of Michigan , 428 Church Street , Ann Arbor , Michigan 48109-1065 , United States.
  • Paixão P; Department of Engineering, Pharmacy Section , Miguel Hernandez University , San Juan de Alicante, 03550 Alicante , Spain.
  • Hens B; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy , Universidade de Lisboa , Avenida Professor Gama Pinto , 1649-003 Lisboa , Portugal.
  • Tsume Y; Department of Pharmaceutical Sciences, College of Pharmacy , University of Michigan , 428 Church Street , Ann Arbor , Michigan 48109-1065 , United States.
  • Koenigsknecht MJ; Department of Pharmaceutical and Pharmacological Sciences , KU Leuven , Herestraat 49 , 3000 Leuven , Belgium.
  • Baker JR; Department of Pharmaceutical Sciences, College of Pharmacy , University of Michigan , 428 Church Street , Ann Arbor , Michigan 48109-1065 , United States.
  • Hasler WL; Department of Pharmaceutical Sciences, College of Pharmacy , University of Michigan , 428 Church Street , Ann Arbor , Michigan 48109-1065 , United States.
  • Dickens J; Office of Generic Drugs, Center for Drug Evaluation and Research , U.S. Food and Drug Administration , Silver Spring , Maryland 20993 , United States.
  • Shedden K; Office of Generic Drugs, Center for Drug Evaluation and Research , U.S. Food and Drug Administration , Silver Spring , Maryland 20993 , United States.
  • Löbenberg R; Department of Pharmaceutical Sciences, College of Pharmacy , University of Michigan , 428 Church Street , Ann Arbor , Michigan 48109-1065 , United States.
  • Lee A; Department of Pharmaceutical Sciences, College of Pharmacy , University of Michigan , 428 Church Street , Ann Arbor , Michigan 48109-1065 , United States.
  • Frances A; Faculty of Pharmacy & Pharmaceutical Sciences , University of Alberta , Edmonton , Alberta , Canada T6G 2H7.
  • Amidon GE; Department of Pharmaceutical Sciences, College of Pharmacy , University of Michigan , 428 Church Street , Ann Arbor , Michigan 48109-1065 , United States.
  • Yu A; Department of Pharmaceutical Sciences, College of Pharmacy , University of Michigan , 428 Church Street , Ann Arbor , Michigan 48109-1065 , United States.
  • Salehi N; Department of Pharmaceutical Sciences, College of Pharmacy , University of Michigan , 428 Church Street , Ann Arbor , Michigan 48109-1065 , United States.
  • Talattof A; Department of Pharmaceutical Sciences, College of Pharmacy , University of Michigan , 428 Church Street , Ann Arbor , Michigan 48109-1065 , United States.
  • Benninghoff G; Center for the Study of Complex Systems and Department of Chemical Engineering , University of Michigan , Ann Arbor , Michigan 48109-2136 , United States.
  • Sun D; Department of Pharmaceutical Sciences, College of Pharmacy , University of Michigan , 428 Church Street , Ann Arbor , Michigan 48109-1065 , United States.
  • Kuminek G; Department of Pharmaceutical Sciences, College of Pharmacy , University of Michigan , 428 Church Street , Ann Arbor , Michigan 48109-1065 , United States.
  • Cavanagh KL; Department of Pharmaceutical Sciences, College of Pharmacy , University of Michigan , 428 Church Street , Ann Arbor , Michigan 48109-1065 , United States.
  • Rodríguez-Hornedo N; Department of Pharmaceutical Sciences, College of Pharmacy , University of Michigan , 428 Church Street , Ann Arbor , Michigan 48109-1065 , United States.
  • Amidon GL; Department of Pharmaceutical Sciences, College of Pharmacy , University of Michigan , 428 Church Street , Ann Arbor , Michigan 48109-1065 , United States.
Mol Pharm ; 15(12): 5454-5467, 2018 12 03.
Article em En | MEDLINE | ID: mdl-30372084
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ibuprofeno / Jejum / Trato Gastrointestinal / Liberação Controlada de Fármacos / Absorção Gastrointestinal Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ibuprofeno / Jejum / Trato Gastrointestinal / Liberação Controlada de Fármacos / Absorção Gastrointestinal Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article