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Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits.
Gilly, Arthur; Suveges, Daniel; Kuchenbaecker, Karoline; Pollard, Martin; Southam, Lorraine; Hatzikotoulas, Konstantinos; Farmaki, Aliki-Eleni; Bjornland, Thea; Waples, Ryan; Appel, Emil V R; Casalone, Elisabetta; Melloni, Giorgio; Kilian, Britt; Rayner, Nigel W; Ntalla, Ioanna; Kundu, Kousik; Walter, Klaudia; Danesh, John; Butterworth, Adam; Barroso, Inês; Tsafantakis, Emmanouil; Dedoussis, George; Moltke, Ida; Zeggini, Eleftheria.
Afiliação
  • Gilly A; Department of Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, United Kingdom.
  • Suveges D; Department of Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, United Kingdom.
  • Kuchenbaecker K; Department of Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, United Kingdom.
  • Pollard M; Division of Psychiatry, University College of London, London, W1T 7NF, United Kingdom.
  • Southam L; UCL Genetics Institute, University College London, London, WC1E 6BT, United Kingdom.
  • Hatzikotoulas K; Department of Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, United Kingdom.
  • Farmaki AE; Department of Medicine, Addenbrooke's Hospital, University of Cambridge, Hills Road, Cambridge, CB2 0QQ, United Kingdom.
  • Bjornland T; Department of Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, United Kingdom.
  • Waples R; Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, United Kingdom.
  • Appel EVR; Department of Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, United Kingdom.
  • Casalone E; Institute of Translational Genomics, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, D-85764, Germany.
  • Melloni G; Department of Health Sciences, College of Life Sciences, University of Leicester, Leicester, LE1 6TP, United Kingdom.
  • Kilian B; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University of Athens, Athens, 176-71, Greece.
  • Rayner NW; Department of Mathematical Sciences, Norwegian Institute of Science and Technology, Trondheim, 7491, Norway.
  • Ntalla I; The Bioinformatics Centre, Department of Biology, University of Copenhagen, Copenhagen, 2200, Denmark.
  • Kundu K; Section for Metabolic Genetics, Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, 2200, Denmark.
  • Walter K; Human Genetics Foundation, University of Torino, Torino, IT-10126, Italy.
  • Danesh J; Department of Biomedical Informatics, Harvard Medical School, Boston, 02115, MA, USA.
  • Butterworth A; Department of Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, United Kingdom.
  • Barroso I; Department of Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, United Kingdom.
  • Tsafantakis E; Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, United Kingdom.
  • Dedoussis G; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Old Road, Headington, Oxford, OX3 7LE, United Kingdom.
  • Moltke I; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, United Kingdom.
  • Zeggini E; Department of Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, United Kingdom.
Nat Commun ; 9(1): 4674, 2018 11 07.
Article em En | MEDLINE | ID: mdl-30405126
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Característica Quantitativa Herdável / Alelos / Sequenciamento Completo do Genoma Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Característica Quantitativa Herdável / Alelos / Sequenciamento Completo do Genoma Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article