Your browser doesn't support javascript.
loading
Deuterium isotope effects in drug pharmacokinetics II: Substrate-dependence of the reaction mechanism influences outcome for cytochrome P450 cleared drugs.
Sun, Hao; Piotrowski, David W; Orr, Suvi T M; Warmus, Joseph S; Wolford, Angela C; Coffey, Steven B; Futatsugi, Kentaro; Zhang, Yinsheng; Vaz, Alfin D N.
Afiliação
  • Sun H; Medicine Design, Pfizer Global Research and Development, Groton, Connecticut, United States of America.
  • Piotrowski DW; Medicine Design, Pfizer Global Research and Development, Groton, Connecticut, United States of America.
  • Orr STM; Medicine Design, Pfizer Global Research and Development, Groton, Connecticut, United States of America.
  • Warmus JS; Medicine Design, Pfizer Global Research and Development, Groton, Connecticut, United States of America.
  • Wolford AC; Medicine Design, Pfizer Global Research and Development, Groton, Connecticut, United States of America.
  • Coffey SB; Medicine Design, Pfizer Global Research and Development, Groton, Connecticut, United States of America.
  • Futatsugi K; Medicine Design, Pfizer Global Research and Development, Groton, Connecticut, United States of America.
  • Zhang Y; Medicine Design, Pfizer Global Research and Development, Groton, Connecticut, United States of America.
  • Vaz ADN; Medicine Design, Pfizer Global Research and Development, Groton, Connecticut, United States of America.
PLoS One ; 13(11): e0206279, 2018.
Article em En | MEDLINE | ID: mdl-30427871
Assuntos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Farmacocinética / Deutério / Citocromo P-450 CYP3A / Citocromo P-450 CYP2C19 Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Farmacocinética / Deutério / Citocromo P-450 CYP3A / Citocromo P-450 CYP2C19 Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article