Assembly of glycoamino acid building blocks: a new strategy for the straightforward synthesis of heparan sulfate mimics.
Chem Commun (Camb)
; 54(95): 13455-13458, 2018 Nov 27.
Article
em En
| MEDLINE
| ID: mdl-30431033
A new strategy that enables a modular straightforward synthesis of heparan sulfate oligosaccharide mimics by the assembly of simple glycoamino acid building blocks is described. The coupling between units is readily carried out by an amidation reaction. Several glycoamino acid oligomers were prepared and their interaction with the FGF2 protein was analyzed.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article