Predictive value of lymphangiogenesis and proliferation markers on mRNA level in urothelial carcinoma of the bladder after radical cystectomy.

Martini, Thomas; Heinkele, Jakob; Mayr, Roman; Weis, Cleo-Aron; Wezel, Felix; Wahby, Sarah; Eckstein, Markus; Schnöller, Thomas; Breyer, Johannes; Wirtz, Ralph; Ritter, Manuel; Bolenz, Christian; Erben, Philipp

Martini, Thomas; Heinkele, Jakob; Mayr, Roman; Weis, Cleo-Aron; Wezel, Felix; Wahby, Sarah; Eckstein, Markus; Schnöller, Thomas; Breyer, Johannes; Wirtz, Ralph; Ritter, Manuel; Bolenz, Christian; Erben, Philipp.

Afiliação

Martini T; Department of Urology, University of Ulm, Ulm, Germany. Electronic address: thomas.martini@uniklinik-ulm.de.
Heinkele J; Department of Urology, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
Mayr R; Department of Urology, University of Regensburg, Caritas St. Josef Medical Center, Germany.
Weis CA; Institute of Pathology, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
Wezel F; Department of Urology, University of Ulm, Ulm, Germany.
Wahby S; Department of Urology, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
Eckstein M; Institute of Pathology, University of Erlangen-Nüremberg, Erlangen, Germany.
Schnöller T; Department of Urology, University of Ulm, Ulm, Germany.
Breyer J; Department of Urology, University of Regensburg, Caritas St. Josef Medical Center, Germany.
Wirtz R; STRATIFYER Molecular Pathology GmbH, Cologne, Germany; Institute of Pathology, The St. Elisabeth Hospital Köln-Hohenlind, Cologne, Germany.
Ritter M; Department of Urology, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
Bolenz C; Department of Urology, University of Ulm, Ulm, Germany.
Erben P; Department of Urology, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany. Electronic address: philipp.erben@medma.uni-heidelberg.de.

Urol Oncol ; 36(12): 530.e19-530.e27, 2018 12.

Article em En | MEDLINE | ID: mdl-30446441

Assuntos

Biomarcadores Tumorais/genética; Proliferação de Células; Cistectomia/efeitos adversos; Linfangiogênese; Recidiva Local de Neoplasia/cirurgia; RNA Mensageiro/genética; Neoplasias da Bexiga Urinária/cirurgia; Idoso; Idoso de 80 Anos ou mais; Biomarcadores Tumorais/metabolismo; Estudos de Coortes; Feminino; Seguimentos; Proteínas Ativadoras de GTPase/genética; Proteínas Ativadoras de GTPase/metabolismo; Humanos; Antígeno Ki-67/genética; Antígeno Ki-67/metabolismo; Metástase Linfática; Masculino; Pessoa de Meia-Idade; Invasividade Neoplásica; Recidiva Local de Neoplasia/patologia; Valor Preditivo dos Testes; RNA Mensageiro/metabolismo; Taxa de Sobrevida; Neoplasias da Bexiga Urinária/patologia; Fator C de Crescimento do Endotélio Vascular/genética; Fator C de Crescimento do Endotélio Vascular/metabolismo; Fator D de Crescimento do Endotélio Vascular/genética; Fator D de Crescimento do Endotélio Vascular/metabolismo; Receptor 3 de Fatores de Crescimento do Endotélio Vascular/genética; Receptor 3 de Fatores de Crescimento do Endotélio Vascular/metabolismo

Palavras-chave

Lymph-specific marker; Proliferation marker; Urothelial carcinoma of the bladder; mRNA expression

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Bexiga Urinária / RNA Mensageiro / Biomarcadores Tumorais / Cistectomia / Linfangiogênese / Proliferação de Células / Recidiva Local de Neoplasia Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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