Activation of Toll-like receptor 7 signaling in labial salivary glands of primary Sjögren's syndrome patients.

Shimizu, T; Nakamura, H; Takatani, A; Umeda, M; Horai, Y; Kurushima, S; Michitsuji, T; Nakashima, Y; Kawakami, A

Shimizu, T; Nakamura, H; Takatani, A; Umeda, M; Horai, Y; Kurushima, S; Michitsuji, T; Nakashima, Y; Kawakami, A.

Afiliação

Shimizu T; Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Nakamura H; Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Takatani A; Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Umeda M; Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Horai Y; Clinical Research Center, National Hospital Organization Nagasaki Medical Center, Omura, Japan.
Kurushima S; Department of Rheumatology, Sasebo Chuo Hospital, Sasebo, Japan.
Michitsuji T; Department of General and Internal Medicine, National Hospital Organization Nagasaki Medical Center, Omura, Japan.
Nakashima Y; Department of Rheumatology, Sasebo City Medical Center, Sasebo, Japan.
Kawakami A; Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.

Clin Exp Immunol ; 196(1): 39-51, 2019 04.

Article em En | MEDLINE | ID: mdl-30446998

Assuntos

Células Epiteliais/fisiologia; Lábio/patologia; Glândulas Salivares/fisiologia; Sialadenite/imunologia; Síndrome de Sjogren/imunologia; Receptor 7 Toll-Like/metabolismo; Idoso; Células Cultivadas; Feminino; Humanos; Fator Regulador 7 de Interferon/metabolismo; Interferon-alfa/metabolismo; Interferon beta/metabolismo; Peptídeos e Proteínas de Sinalização Intracelular/genética; Peptídeos e Proteínas de Sinalização Intracelular/metabolismo; Masculino; Pessoa de Meia-Idade; Fator 88 de Diferenciação Mieloide/metabolismo; Transdução de Sinais

Palavras-chave

Sjögren's syndrome; TLR-7; plasmacytoid dendritic cells; type I interferons

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glândulas Salivares / Sialadenite / Síndrome de Sjogren / Células Epiteliais / Receptor 7 Toll-Like / Lábio Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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