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A small molecule approach to degrade RAS with EGFR repression is a potential therapy for KRAS mutation-driven colorectal cancer resistance to cetuximab.
Lee, Sang-Kyu; Cho, Yong-Hee; Cha, Pu-Hyeon; Yoon, Jeong-Soo; Ro, Eun Ji; Jeong, Woo-Jeong; Park, Jieun; Kim, Hyuntae; Il Kim, Tae; Min, Do Sik; Han, Gyoonhee; Choi, Kang-Yell.
Afiliação
  • Lee SK; Translational Research Center for Protein Function Control, Yonsei University, Seoul, Korea.
  • Cho YH; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea.
  • Cha PH; Translational Research Center for Protein Function Control, Yonsei University, Seoul, Korea.
  • Yoon JS; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea.
  • Ro EJ; Translational Research Center for Protein Function Control, Yonsei University, Seoul, Korea.
  • Jeong WJ; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea.
  • Park J; Translational Research Center for Protein Function Control, Yonsei University, Seoul, Korea.
  • Kim H; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea.
  • Il Kim T; Translational Research Center for Protein Function Control, Yonsei University, Seoul, Korea.
  • Min DS; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea.
  • Han G; Translational Research Center for Protein Function Control, Yonsei University, Seoul, Korea.
  • Choi KY; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea.
Exp Mol Med ; 50(11): 1-12, 2018 11 20.
Article em En | MEDLINE | ID: mdl-30459318
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Proteínas Proto-Oncogênicas p21(ras) / Resistencia a Medicamentos Antineoplásicos / Receptores ErbB / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Proteínas Proto-Oncogênicas p21(ras) / Resistencia a Medicamentos Antineoplásicos / Receptores ErbB / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article