Genetic disorders in primary brain glioblastomas.
Vopr Onkol
; 62(4): 471-8, 2016.
Article
em Ru
| MEDLINE
| ID: mdl-30475532
ABSTRACT
Glioblastomas are characterized by a variety of genetic and epigenetic disorders, identification of which allows constantly expanding a list of genes directly involved in carcinogenesis, thus increasing molecular diagnostics, monitoring and predicting disease. Molecular-genetic studies of patients with glioblastomas allowed revealing changes relevant to this disease and determining their prognostic significance. In the future molecular-biological markers along with clinical and therapeutic factors may play a role of separate and independent factors of prognosis in patients with malignant brain lesions.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Prognóstico
/
Biomarcadores Tumorais
/
Glioblastoma
/
Carcinogênese
Tipo de estudo:
Prognostic_studies
Limite:
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Ru
Ano de publicação:
2016
Tipo de documento:
Article