Targeting peptidylarginine deiminase reduces neutrophil extracellular trap formation and tissue injury in severe acute pancreatitis.

Madhi, Raed; Rahman, Milladur; Taha, Dler; Mörgelin, Matthias; Thorlacius, Henrik

Madhi, Raed; Rahman, Milladur; Taha, Dler; Mörgelin, Matthias; Thorlacius, Henrik.

Afiliação

Madhi R; Department of Surgery, Clinical Sciences, Malmö, Skåne University Hospital, Lund University, Lund, Sweden.
Rahman M; Department of Surgery, Clinical Sciences, Malmö, Skåne University Hospital, Lund University, Lund, Sweden.
Taha D; Department of Surgery, Clinical Sciences, Malmö, Skåne University Hospital, Lund University, Lund, Sweden.
Mörgelin M; Department of Surgery, Clinical Sciences, Malmö, Skåne University Hospital, Lund University, Lund, Sweden.
Thorlacius H; Department of Surgery, Clinical Sciences, Malmö, Skåne University Hospital, Lund University, Lund, Sweden.

J Cell Physiol ; 234(7): 11850-11860, 2019 07.

Article em En | MEDLINE | ID: mdl-30515825

Assuntos

Armadilhas Extracelulares/metabolismo; Infiltração de Neutrófilos/fisiologia; Neutrófilos/metabolismo; Pancreatite/metabolismo; Doença Aguda; Animais; Quimiocina CXCL2/metabolismo; Quimiocinas/sangue; Quimiocinas/metabolismo; Interleucina-6/sangue; Masculino; Camundongos Endogâmicos C57BL; Pâncreas/metabolismo; Peroxidase/metabolismo; Desiminases de Arginina em Proteínas/metabolismo

Palavras-chave

chemokines; histones; inflammation; leukocyte and pancreas

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pancreatite / Infiltração de Neutrófilos / Armadilhas Extracelulares / Neutrófilos Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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