Allele-specific genome editing using CRISPR-Cas9 is associated with loss of heterozygosity in diploid yeast.

Gorter de Vries, Arthur R; Couwenberg, Lucas G F; van den Broek, Marcel; de la Torre Cortés, Pilar; Ter Horst, Jolanda; Pronk, Jack T; Daran, Jean-Marc G

Gorter de Vries, Arthur R; Couwenberg, Lucas G F; van den Broek, Marcel; de la Torre Cortés, Pilar; Ter Horst, Jolanda; Pronk, Jack T; Daran, Jean-Marc G.

Afiliação

Gorter de Vries AR; Department of Biotechnology, Delft University of Technology, Delft 2629HZ, The Netherlands.
Couwenberg LGF; Department of Biotechnology, Delft University of Technology, Delft 2629HZ, The Netherlands.
van den Broek M; Department of Biotechnology, Delft University of Technology, Delft 2629HZ, The Netherlands.
de la Torre Cortés P; Department of Biotechnology, Delft University of Technology, Delft 2629HZ, The Netherlands.
Ter Horst J; Department of Biotechnology, Delft University of Technology, Delft 2629HZ, The Netherlands.
Pronk JT; Department of Biotechnology, Delft University of Technology, Delft 2629HZ, The Netherlands.
Daran JG; Department of Biotechnology, Delft University of Technology, Delft 2629HZ, The Netherlands.

Nucleic Acids Res ; 47(3): 1362-1372, 2019 02 20.

Article em En | MEDLINE | ID: mdl-30517747

Assuntos

Sistemas CRISPR-Cas/genética; Diploide; Edição de Genes; Perda de Heterozigosidade/genética; Alelos; Proliferação de Células/genética; Quebras de DNA de Cadeia Dupla; Heterozigoto; Homozigoto; Humanos; Saccharomyces cerevisiae/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Perda de Heterozigosidade / Diploide / Sistemas CRISPR-Cas / Edição de Genes Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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