MGMT is down-regulated independently of promoter DNA methylation in rats with all-trans retinoic acid-induced spina bifida aperta.

Zhang, He-Nan; Guo, Yi; Ma, Wei; Xue, Jia; Wang, Wei-Lin; Yuan, Zheng-Wei

Zhang, He-Nan; Guo, Yi; Ma, Wei; Xue, Jia; Wang, Wei-Lin; Yuan, Zheng-Wei.

Afiliação

Zhang HN; Key Laboratory of Health Ministry for Congenital Malformation, Shengjing Hospital, China Medical University, Shenyang, Liaoning Province, China.
Guo Y; Key Laboratory of Health Ministry for Congenital Malformation, Shengjing Hospital, China Medical University, Shenyang, Liaoning Province, China.
Ma W; Key Laboratory of Health Ministry for Congenital Malformation, Shengjing Hospital, China Medical University, Shenyang, Liaoning Province, China.
Xue J; Key Laboratory of Health Ministry for Congenital Malformation, Shengjing Hospital, China Medical University, Shenyang, Liaoning Province, China.
Wang WL; Department of Pediatric Surgery, Shengjing Hospital, China Medical University, Shenyang, Liaoning Province, China.
Yuan ZW; Key Laboratory of Health Ministry for Congenital Malformation, Shengjing Hospital, China Medical University, Shenyang, Liaoning Province, China.

Neural Regen Res ; 14(2): 361-368, 2019 Feb.

Article em En | MEDLINE | ID: mdl-30531021

Palavras-chave

DNA methylation; O6-methylguanine DNA methyl-transferase; all-trans retinoic acid; bisulfite sequencing polymerase chain reaction; gene expression; nerve regeneration; neural regeneration; neural tube defects; promoter; spina bifida aperta; spinal cord

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2019 Tipo de documento: Article