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Isavuconazole in the Treatment of Coccidioidal Meningitis.
Heidari, Arash; Quinlan, Miriam; Benjamin, David J; Laurence, Brett; Mu, Anandit; Ngai, Tiffany; Hoffman, Wes J; Cohen, Stuart H; McHardy, Ian; Johnson, Royce; Thompson, George R.
Afiliação
  • Heidari A; Kern County Medical Center, Bakersfield, California, USA.
  • Quinlan M; Valley Fever Institute, Bakersfield, California, USA.
  • Benjamin DJ; Kern County Medical Center, Bakersfield, California, USA.
  • Laurence B; Department of Internal Medicine, University of California Davis Medical Center, Sacramento, California, USA.
  • Mu A; Sutter Medical Center, Sacramento, California, USA.
  • Ngai T; Department of Internal Medicine, Division of Infectious Diseases, University of California San Francisco-Fresno, Fresno, California, USA.
  • Hoffman WJ; Department of Internal Medicine, Division of Infectious Diseases, University of California San Francisco-Fresno, Fresno, California, USA.
  • Cohen SH; Department of Pharmacy, University of California Davis Medical Center, Sacramento, California, USA.
  • McHardy I; Department of Internal Medicine, Division of Infectious Diseases, University of California Davis Medical Center, Sacramento, California, USA.
  • Johnson R; Department of Medical Microbiology and Immunology, University of California Davis, Davis, California, USA.
  • Thompson GR; Kern County Medical Center, Bakersfield, California, USA.
Antimicrob Agents Chemother ; 63(3)2019 03.
Article em En | MEDLINE | ID: mdl-30559134
ABSTRACT
Patients with coccidioidal meningitis require lifelong antifungal therapy. Cumulative toxicity and lack of antifungal efficacy require salvage therapy in the treatment of some patients. In a retrospective review of nine patients with coccidioidal meningitis treated with isavuconazole, successful therapy was seen in three patients and stable disease was confirmed in six patients. Isavuconazole may be a useful addition to the therapeutic choices currently available for coccidioidal meningitis.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piridinas / Triazóis / Meningite Fúngica / Coccidioidomicose / Antifúngicos / Nitrilas Tipo de estudo: Observational_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piridinas / Triazóis / Meningite Fúngica / Coccidioidomicose / Antifúngicos / Nitrilas Tipo de estudo: Observational_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2019 Tipo de documento: Article