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Persistent arterial wall inflammation in patients with elevated lipoprotein(a) despite strong low-density lipoprotein cholesterol reduction by proprotein convertase subtilisin/kexin type 9 antibody treatment.
Stiekema, Lotte C A; Stroes, Erik S G; Verweij, Simone L; Kassahun, Helina; Chen, Lisa; Wasserman, Scott M; Sabatine, Marc S; Mani, Venkatesh; Fayad, Zahi A.
Afiliação
  • Stiekema LCA; Department of Vascular Medicine, Amsterdam University Medical Center, University of Amsterdam, Meibergdreef 9, AZ Amsterdam, The Netherlands.
  • Stroes ESG; Department of Vascular Medicine, Amsterdam University Medical Center, University of Amsterdam, Meibergdreef 9, AZ Amsterdam, The Netherlands.
  • Verweij SL; Department of Vascular Medicine, Amsterdam University Medical Center, University of Amsterdam, Meibergdreef 9, AZ Amsterdam, The Netherlands.
  • Kassahun H; Department of Clinical Development, Amgen Inc., One Amgen Center Drive Thousand Oaks, CA, USA.
  • Chen L; Department of Biostatistics, Amgen Inc., One Amgen Center Drive Thousand Oaks, CA, USA.
  • Wasserman SM; Department of Clinical Development, Amgen Inc., One Amgen Center Drive Thousand Oaks, CA, USA.
  • Sabatine MS; Division of Cardiovascular Medicine, TIMI Study Group, Brigham and Women's Hospital and Harvard Medical School, Fenwood Road, Boston, MA, USA.
  • Mani V; Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Pl, New York, NY, USA.
  • Fayad ZA; Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Pl, New York, NY, USA.
Eur Heart J ; 40(33): 2775-2781, 2019 09 01.
Article em En | MEDLINE | ID: mdl-30561610
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Arterite / Lipoproteína(a) / Anticorpos Monoclonais Humanizados / Pró-Proteína Convertase 9 / LDL-Colesterol / Anticolesterolemiantes Tipo de estudo: Clinical_trials Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2019 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Arterite / Lipoproteína(a) / Anticorpos Monoclonais Humanizados / Pró-Proteína Convertase 9 / LDL-Colesterol / Anticolesterolemiantes Tipo de estudo: Clinical_trials Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2019 Tipo de documento: Article